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DEPE | Stratégie scientifique » adaptations Physiologiques À la GRAvité & Santé (PAGRAS) » Audrey Bergouignan

Audrey Bergouignan

Dernière mise à jour : mercredi 8 janvier 2020, par Audrey Bergouignan

Research summary

It is becoming increasingly evident that sedentary behaviors play an independent and critical role in alterations of metabolic health. Any strategy that prevents these adverse consequences would thus represent a major public health progress. Our research goals are to understand the mechanisms by which sedentary behaviors contribute to the development and progression of metabolic diseases and to develop preventive strategies for the metabolic alterations induced by sedentariness. The first axis of research is investigating the physiology of sedentary behaviors and physical inactivity by using an integrative approach studying the different levels of integration from the whole-body level to organ, cell, protein and genes in controlled lab-setting studies (bed-rest studies and reduced physical activity). The second axis of research aims at developing and implementing novel practical and cost-effective strategies to reduce time spent in sedentary activities and promote physical activity in the real world including at work. We are currently testing the efficacy and feasibility of microbursts of activity by comparison to traditional exercise to reduce time spent sitting and improve metabolism. In a translational perspective, the ultimate goal is to bring objective and convincing evidence to help refining public health and occupational health guidelines.

Research themes

Energy and nutrient metabolism
Physical inactivity
Sedentary behaviors
Integrative physiology

Full CV

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Curriculum Vitae of Audrey BERGOUIGNAN, Ph.D.

2016 CR1 Researcher, Institut Plurisdiciplinaire Hubert Curien, Département d’Écologie, Physiology, Éthologie, Strasbourg, France
2014-2016 Senior Post-doc fellow, University of Colorado, Denver, Colorado, USA
2013-2014 Visiting scientist, Baker Heart & Diabetes Institute, Melbourne, Australia
2009-2013 Post-doc fellow, University of Colorado, Denver, Colorado, USA
2008 PhD in Physiology and Biology of Organisms, Université Louis Pasteur, Strasbourg, France

Lab members

Stéphane Blanc
Isabelle Chery
Alexandre Zahariev
Anthony Damiot