Annuaire IPHC

DSA | Spectrométrie de Masse BioOrganique (LSMBO) » Publications



Ibrahim M, Ayoub D, Wasselin T, Van Dorsselaer A, Le Maho Y, Raclot T, Bertile F. 2020. Alterations in rat adipose tissue transcriptome and proteome in response to prolonged fasting. Biological Chemistry 401:389-405.

Laurens C, Parmar A, Murphy E, Carper D, Lair B, Maes P, Vion J, Boulet N, Fontaine C, Marquès M, Larrouy D, Harant I, Thalamas C, Montastier E, Caspar-Baugil S, Bourlier V, Tavernier G, Grolleau JL, Bouloumié A, Langin D, Viguerie N, Bertile F, Blanc S, De Glisezinski I, O’Gorman D, Moro C. 2020. Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans. JCI Insight 5:E131870,

Luu BE, Lefai E, Giroud S, Swenson JE, Chazarin B, Gauquelin-Koch G, Arnemo JM, Evans AL, Bertile F, Storey KB. 2020. MicroRNAs facilitate skeletal muscle maintenance and metabolic suppression in hibernating brown bears. J Cell Physiol 235:3984-3993,

Allison TM, Barran PE, Benesch JLP, Cianferani S, Degiacomi MT, Gabelica V, Grandori R, Marklund EG, Menneteau T, Migas LG, Politis A, Sharon M, Sobott F, Thalassinos K. 2020. Software requirements for the analysis and interpretation of native ion mobility mass spectrometry data. Anal Chem,

Allison TM, Barran PE, Cianferani S, Degiacomi MT, Gabelica V, Grandori R, Marklund EG, Menneteau T, Migas LG, Politis A, Sharon M, Sobott F, Thalassinos K, Benesch JLP. 2020. Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology. Anal Chem,

Botzanowski T, Hernandez-Alba O, Malissard M, Wagner-Rousset E, Desligniere E, Colas O, Haeuw JF, Beck A, Cianferani S. 2020. Middle Level IM-MS and CIU Experiments for Improved Therapeutic Immunoglobulin Subclass Fingerprinting. Anal Chem 92:8827-8835,

Bouyssié D, Hesse AM, Mouton-Barbosa E, Rompais M, Macron C, Carapito C, Gonzalez de Peredo A, Couté Y, Dupierris V, Burel A, Menetrey JP, Kalaitzakis A, Poisat J, Romdhani A, Burlet-Schiltz O, Cianférani S, Garin J, Bruley C. 2020. Proline : an efficient and user-friendly software suite for large-scale proteomics. Bioinformatics, btaa118,

Chabrol E, Stojko J, Nicolas A, Botzanowski T, Fould B, Antoine M, Cianferani S, Ferry G, Boutin JA. 2020. VHH characterization.Recombinant VHHs : Production, characterization and affinity. Anal Biochem 589:113491,

Ciudad S, Puig E, Botzanowski T, Meigooni M, Arango AS, Do J, Mayzel M, Bayoumi M, Chaignepain S, Maglia G, Cianferani S, Orekhov V, Tajkhorshid E, Bardiaux B, Carulla N. 2020. Abeta(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage. Nat Commun 11:3014,

Dovgan I, Ehkirch A, Lehot V, Kuhn I, Koniev O, Kolodych S, Hentz A, Ripoll M, Ursuegui S, Nothisen M, Cianferani S, Wagner A. 2020. On the use of DNA as a linker in antibody-drug conjugates : synthesis, stability and in vitro potency. Sci Rep 10:7691,

Duivelshof BL, Desligniere E, Hernandez-Alba O, Ehkirch A, Toftevall H, Sjogren J, Cianferani S, Beck A, Guillarme D, D’Atri V. 2020. Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody-Drug Conjugates : Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS Analysis. Anal Chem 92:8170-8177,

Farras M, Miret J, Camps M, Roman R, Martinez O, Pujol X, Erb S, Ehkirch A, Cianferani S, Casablancas A, Cairo JJ. 2020. Homogeneous antibody-drug conjugates : DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly. MAbs 12:1702262,

Hernandez-Alba O, Ehkirch A, Beck A, Cianferani S. 2020. Analysis of ADCs by Native Mass Spectrometry. Methods Mol Biol 2078:197-211,

Humbert N, Kovalenko L, Saladini F, Giannini A, Pires M, Botzanowski T, Cherenok S, Boudier C, Sharma KK, Real E, Zaporozhets OA, Cianferani S, Seguin-Devaux C, Poggialini F, Botta M, Zazzi M, Kalchenko VI, Mori M, Mely Y. 2020. (Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity. ACS Infect Dis 6:687-702,

Postic G, Marcoux J, Reys V, Andreani J, Vandenbrouck Y, Bousquet MP, Mouton-Barbosa E, Cianferani S, Burlet-Schiltz O, Guerois R, Labesse G, Tuffery P. 2020. Probing Protein Interaction Networks by Combining MS-Based Proteomics and Structural Data Integration. J Proteome Res 19:2807-2820,

Sabou M, Doderer-Lang C, Leyer C, Konjic A, Kubina S, Lennon S, Rohr O, Viville S, Cianferani S, Candolfi E, Pfaff AW, Brunet J. 2020. Toxoplasma gondii ROP16 kinase silences the cyclin B1 gene promoter by hijacking host cell UHRF1-dependent epigenetic pathways. Cell Mol Life Sci 77:2141-2156,

Sornay C, Hessmann S, Erb S, Dovgan I, Ehkirch A, Botzanowski T, Cianferani S, Wagner A, Chaubet G. 2020. Investigating Ugi / Passerini multicomponent reactions for the Site-Selective Conjugation of Native Trastuzumab. Chemistry,

Tessier R, Nandi RK, Dwyer BG, Abegg D, Sornay C, Ceballos J, Erb S, Cianferani S, Wagner A, Chaubet G, Adibekian A, Waser J. 2020. Ethynylation of Cysteine Residues : From Peptides to Proteins in Vitro and in Living Cells. Angew Chem Int Ed Engl 59:10961-10970,

Wagner E, Colas O, Chenu S, Goyon A, Murisier A, Cianferani S, Francois Y, Fekete S, Guillarme D, D’Atri V, Beck A. 2020. Determination of size variants by CE-SDS for approved therapeutic antibodies : Key implications of subclasses and light chain specificities. J Pharm Biomed Anal 184:113166,

Wagner-Rousset E, Colas O, Francois YN, Heinisch S, Guillarme D, Cianferani S, Beck A. 2020. Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction. Methods Mol Biol 2078:187-195,

Kenny HC, Tascher G, Ziemianin A, Rudwill F, Zahariev A, Chery I, Gauquelin-Koch G, Barielle MP, Heer M, Blanc S, O’Gorman DJ, Bertile F. 2020. Effectiveness of Resistive Vibration Exercise and Whey Protein Supplementation Plus Alkaline Salt on the Skeletal Muscle Proteome Following 21 Days of Bed Rest in Healthy Males. J Proteome Res 19:3438-3451,

Bernard Q, Grillon A, Lenormand C, Ehret-Sabatier L, Boulanger N. 2020. Skin Interface, a Key Player for Borrelia Multiplication and Persistence in Lyme Borreliosis. Trends in Parasitology In press

Lefeuvre B, Cantero P, Ehret-Sabatier L, Lenormand C, Barthel C, Po C, Parveen N, Grillon A, Jaulhac B, Boulanger N. 2020. Effects of topical corticosteroids and lidocaine on Borrelia burgdorferi sensu lato in mouse skin : potential impact to human clinical trials. Sci Rep 10:10552,

Perraud Q, Cantero P, Roche B, Gasser V, Normant VP, Kuhn L, Hammann P, Mislin GLA, Ehret-Sabatier L, Schalk IJ. 2020. Phenotypic Adaption of Pseudomonas aeruginosa by Hacking Siderophores Produced by Other Microorganisms. Mol Cell Proteomics 19:589-607,

Bonnet M, Soulat J, Bons J, Leger S, De Koning L, Carapito C, Picard B. 2020. Quantification of biomarkers for beef meat qualities using a combination of Parallel Reaction Monitoring- and antibody-based proteomics. Food Chem 317:126376.

Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Gross M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S. 2020. NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. J Exp Med 217,

Charles L, Mondal T, Greff V, Razzini M, Monnier V, Burel A, Carapito C, Lutz JF. 2020. Optimal conditions for tandem mass spectrometric sequencing of information-containing nitrogen-substituted polyurethanes. Rapid Commun Mass Spectrom 34:e8815,

Spenle C, Loustau T, Murdamoothoo D, Erne W, Beghelli-de la Forest Divonne S, Veber R, Petti L, Bourdely P, Morgelin M, Brauchle EM, Cremel G, Randrianarisoa V, Camara A, Rekima S, Schaub S, Nouhen K, Imhof T, Hansen U, Paul N, Carapito R, Pythoud N, Hirschler A, Carapito C, Dumortier H, Mueller CG, Koch M, Schenke-Layland K, Kon S, Sudaka A, Anjuere F, Van Obberghen-Schilling E, Orend G. 2020. Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma. Cancer Immunol Res,

Thompson D, Cognat V, Goodfellow M, Koechler S, Heintz D, Carapito C, Van Dorsselaer A, Mahmoud H, Sangal V, Ismail W. 2020. Phylogenomic Classification and Biosynthetic Potential of the Fossil Fuel-Biodesulfurizing Rhodococcus Strain IGTS8. Front Microbiol 11:1417,

Chabrol E, Stojko J, Nicolas A, Botzanowski T, Fould B, Antoine M, Cianferani S, Ferry G, Boutin JA. 2020. VHH characterization.Recombinant VHHs : Production, characterization and affinity. Anal Biochem 589:113491,

Sabou M, Doderer-Lang C, Leyer C, Konjic A, Kubina S, Lennon S, Rohr O, Viville S, Cianferani S, Candolfi E, Pfaff AW, Brunet J. 2020. Toxoplasma gondii ROP16 kinase silences the cyclin B1 gene promoter by hijacking host cell UHRF1-dependent epigenetic pathways. Cell Mol Life Sci 77:2141-2156,


Strassel C, Magiera M, Dupuis A, Batzenschlager M, Hovasse A, Pleines I, Guéguen P, Eckly A, Moog S, Mallo L, Kimmerlin Q, Chappaz S, Strub J, Kathiresan N, de la Salle H, Van Dorsselaer A, Ferec C, Py J, Gachet C, Schaeffer-Reiss C, Kile B, Janke C, Lanza F. 2019. An essential role for α4A-tubulin in platelet biogenesis. Life Sci Alliance 2:pii : e201900309.

Schneider F, Dureau A-F, Hellé S, Betscha C, Senger B, Cremel G, Boulmedais F, Strub JM, Corti A, Meyer N, Guillot M, Schaaf P, Metz-Boutigue MH. 2019. A Pilot Study on Continuous Infusion of 4% Albumin in Critically Ill Patients : Impact on Nosocomial Infection via a Reduction Mechanism for Oxidized Substrates. Critical Care Explorations 1.

Sanchez C, Moliner Cubel S, Nyboer B, Jankowska-Döllken M, Schaeffer-Reiss C, Ayoub D, Planelles G, Lanzer M. 2019. Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum. J Biol Chem.:pii : jbc.RA119.009464.

Sabou M, Doderer-Lang C, Leyer C, Konjic A, Kubina S, Lennon S, Rohr O, Viville S, Cianférani S, Candolfi E, Pfaff A, Brunet J. 2019. Toxoplasma gondii ROP16 kinase silences the cyclin B1 gene promoter by hijacking host cell UHRF1-dependent epigenetic pathways. Cell Mol Life Sci. 2019 Sep 6.

Quque M, Benhaim-Delarbre M, Deneubourg J, Sueur C, Criscuolo F, Bertile F. 2019. Division of labour in the black garden ant (Lasius niger) leads to three distinct proteomes. J Insect Physiol. 117:103907.

Plumel M, Dumont S, Maes P, Sandu C, Felder-Scmittbuhl MP, Challet E, Bertile F. 2019. Circadian Analysis of the Mouse Cerebellum Proteome. International Journal of Molecular Sciences 20:1852.

Niazi A, Bariat L, Riondet C, Carapito C, Mhamdi A, Noctor G, Reichheld J. 2019. Cytosolic Isocitrate Dehydrogenase from Arabidopsis thaliana Is Regulated by Glutathionylation. Antioxidants (Basel) 8:pii : E16.

Muller L, Fornecker L, Cianferani S, Carapito C. 2019. Tube-Gel : A Fast and Effective Sample Preparation Method for High-Throughput Quantitative Proteomics. Methods Mol Biol. 1959:123-127.

Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon M, Machado P, Delalande F, López A, Silva S, Verweij F, van Niel G, Djouad F, Peinado H, Carapito C, Klymchenko A, Goetz J. 2019. Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo. Dev Cell. 48:554-572.e557.

Hernandez-Alba O HS, Hessmann S, Erb S, Rabuka D, Huguet R, Josephs J, Beck A, Drake PM, Cianférani S. 2019. A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry. J Am Soc Mass Spectrom. 30:2419-2429.

Hartmann L, Botzanowski T, Galibert M, Jullian M, Chabrol lE, Zeder-Lutz G, Kugler V, Stojko J, Strub J, Ferry G, Frankiewicz L, Puget K, Wagner R, Cianférani S, Boutin J. 2019. VHH characterization. Comparison of recombinant with chemically synthesized anti-HER2 VHH. Protein Sci. 28:1865-1879.

Groysbeck N, Stoessel A, Donzeau M, da Silva E, Lehmann M, Strub J, Cianferani S, Dembélé K, Zuber G. 2019. Synthesis and biological evaluation of 2.4 nm thiolate-protected gold nanoparticles conjugated to Cetuximab for targeting glioblastoma cancer cells via the EGFR. Nanotechnology 30:184005.

Giroud S, Chery I, F. B, Bertrand-Michel J, Tascher G, Gauquelin-Koch G, Arnemo JM, Swenson JE, Singh NV, Lefai E, Evans AL, Simon C, Blanc S. 2019. Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear. Front Physiol. 10:389.

Gervason S, Larkem D, Mansour A, Botzanowski T, Müller C, Pecqueur L, Le Pavec G, Delaunay-Moisan A, Brun O, Agramunt J, Grandas A, Fontecave M, Schünemann V, Cianférani S, Sizun C, Tolédano M, D’Autréaux B. 2019. Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin. Nat Commun. 10:3566.

Dalzon B, Bons J, Diemer H, Collin-Faure V, Marie-Desvergne C, Dubosson M, Cianferani S, Carapito C, Rabilloud T. 2019. A Proteomic View of Cellular Responses to Anticancer Quinoline-Copper Complexes. Proteomes 7:pii : E26.

Chazarin B, Ziemianin A, Evans AL, Meugnier E, Loizon E, Chery I, Arnemo JM, Swenson JE, Gauquelin-Koch G, Simon C, Blanc S, Lefai E, Bertile F. 2019. Limited oxidative stress favors resistance to skeletal muscle atrophy in hibernating brown bears (Ursus arctos). Antioxidants 8:334.

Chazarin B, Storey K, Ziemianin A, Chanon S, Plumel M, Chery I, Durand C, Evans A, Arnemo J, Zedrosser A, Swenson J, Gauquelin-Koch G, Simon C, Blanc S, Lefai E, Bertile F. 2019. Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle. Front Zool. 16:12.

Bons J, Macron C, Aude-Garcia C, Vaca-Jacome S, Rompais M, Cianférani S, Carapito C, Rabilloud T. 2019. A Combined N-terminomics and Shotgun Proteomics Approach to Investigate the Responses of Human Cells to Rapamycin and Zinc at the Mitochondrial Level. Mol Cell Proteomics 18:1085-1095.

Beck A, D’Atri V, Ehkirch A, Fekete S, Hernandez-Alba O, Gahoual R, Leize-Wagner E, François Y, Guillarme D, Cianférani S. 2019. Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates : present and future. Expert Rev Proteomics. 16:337-362.

 !!! Baxter PNW, Al Ouahabi A, Karmazin L, Varnek A, Strub JM, Cianferani S. 2019. An Investigation into the Stephens-Castro Synthesis of Dehydrotriaryl[12]annulenes : Factors Influencing the Cyclotrimerization. European Journal of Organic Chemistry 40:6783-6795.

Ayala-Nunez N, Follain G, Delalande F, Hirschler A, Partiot E, Hale G, Bollweg B, Roels J, Chazal M, Bakoa F, Carocci M, Bourdoulous S, Faklaris O, Zaki S, Eckly A, Uring-Lambert B, Doussau F, Cianferani S, Carapito C, Jacobs F, Jouvenet N, Goetz J, Gaudin R. 2019. Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells. Nat Commun. 2019 Sep 27 ;10(1):4430.

Tascher G, Gerbaix M, Maes P, Chazarin B, Ghislin S, Antropova E, Vassilieva G, Ouzren-Zarhloul N, Gauquelin-Koch G, Vico L, Frippiat J, Bertile F. 2019. Analysis of femurs from mice embarked on board BION-M1 biosatellite reveals a decrease in immune cell development, including B cells, after 1 wk of recovery on Earth. FASEB J. 33. doi :

Boeuf A, Schnell G, Bernard Q, Kern A, Westermann B, Ehret-Sabatier L, Grillon A, Schramm F, Jaulhac B, Boulanger N. 2019. Dissociating effect of salivary gland extract from Ixodes ricinus on human fibroblasts : Potential impact on Borrelia transmission. Ticks Tick Borne Dis. 10:433–441. doi :

Rochel N, Krucker C, Coutos-Thévenot L, Osz J, Zhang R, Guyon E, Zita W, Vanthong S, Hernandez-Alba O, Bourguet M, Al Badawy K, Dufour F, Peluso-Iltis C, Heckler-Beji S, Dejaegere A, Kamoun A, de Reyniès A, Neuzillet Y, Rebouissou S, Béraud C, Lang H, Massfelder T, Allory Y, Cianférani S, Stote RH, Radvanyi F, Bernard-Pierrot I. 2019. Recurrent activating mutations of PPARγ associated with luminal bladder tumors. Nature Communications 10:253. doi :

Fornecker L, Muller L, Bertrand F, Paul N, Pichot A, Herbrecht R, Chenard M-P, Mauvieux L, Vallat L, Bahram S, Cianférani S, Carapito R, Carapito C. 2019. Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma. Sci. Rep:895. doi :

Tascher G, Burban A, Camus S, Plumel M, Chanon S, Le Guevel R, Shevchenko V, Van Dorsselaer A, Lefai E, Guguen-Guillouzo C, Bertile F. 2019. In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes. Cells 8:192. doi :


Berthier A, Vinod M, Porez G, Steenackers A, Alexandre J, Yamakawa N, Gheeraert C, Ploton M, Maréchal X, Dubois-Chevalier J, Hovasse A, Schaeffer-Reiss C, Cianférani S, Rolando C, Bray F, Duez H, Eeckhoute J, Lefebvre T, Staels B, Lefebvre P. 2018. Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex. Proc Natl Acad Sci U S A. 2018 Nov 5. pii : 201805397. doi :

Carapito R, Carapito C, Morlon A, Paul N, Vaca Jacome A, Alsaleh G, Rolli V, Tahar O, Aouadi I, Rompais M, Delalande F, Pichot A, Georgel P, Messer L, Sibilia J, Cianferani S, Van Dorsselaer A, Bahram S. 2018. Multi-OMICS analyses unveil STAT1 as a potential modifier gene in mevalonate kinase deficiency. Ann Rheum Dis.:pii : annrheumdis-2018-213524. doi :

Coulter M, Dorobantu C, Lodewijk G, Delalande F, Cianferani S, Ganesh V, Smith R, Lim E, Xu C, Pang S, Wong E, Lidov H, Calicchio M, Yang E, Gonzalez D, Schlaeger T, Mochida G, Hess H, Lee W, Lehtinen M, Kirchhausen T, Haussler D, Jacobs F, Gaudin R, Walsh C. 2018. The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Rep. 24:973-986.e978. doi :

Desplancq D, Groysbeck N, Chiper M, Weiss E, Frisch B, Strub J, Cianférani S, Zafeiratos S, Moeglin E, Holy X, Favier aL, Decarlo S, Schultz P, Spehner D, Zuber G. 2018. Cytosolic Diffusion and Peptide-assisted Nuclear Shuttling of Peptide-substituted circa 102 Gold Atom Nanoclusters in Living Cells. ACS Applied Nano Materials 1:4236-4246. doi :

Ehkirch A, Goyon A, Hernandez-Alba O, Rouviere F, D’Atri V, Dreyfus C, Haeuw J, Diemer H, Beck A, Heinisch S, Guillarme D, Cianferani S. 2018. A Novel Online Four-Dimensional SEC×SEC-IM×MS Methodology for Characterization of Monoclonal Antibody Size Variants. Anal Chem. Anal Chem. 2018 Nov 12. doi :

Giroud S, Evans A, Chery I, Bertile F, Tascher G, Bertrand-Michel J, Gauquelin-Koch G, Arnemo J, Swenson J, Lefai E, Blanc S, Simon C. 2018. Seasonal changes in eicosanoid metabolism in the brown bear. Naturwissenschaften 105:58. doi :

Henri J, Chagot M, Bourguet M, Abel Y, Terral G, Maurizy C, Aigueperse C, Georgescauld F, Vandermoere F, Saint-Fort R, Behm-Ansmant I, Charpentier B, Pradet-Balade B, Verheggen C, Bertrand E, Meyer P, Cianférani S, Manival X, Quinternet M. 2018. Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure 26:1196-1209.e1198. doi :

Hernandez-Alba O, Wagner-Rousset E, Beck A, Cianférani S. 2018. Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies. Anal Chem. 90:8865-8872. doi :

Koniev O, Dovgan I, Renoux B, Ehkirch A, Eberova J, S. C, Kolodych S, Papot S, Wagner A. 2018. Reduction-rebridging strategy for the preparation of ADPN-based antibody-drug conjugates. Medchemcomm. 9:827-830. doi :

Mons C, Botzanowski T, Nikolaev A, Hellwig P, Cianférani S, Lescop E, Bouton C, Golinelli-Cohen M. 2018. The H2O2-Resistant Fe-S Redox Switch MitoNEET Acts as a pH Sensor To Repair Stress-Damaged Fe-S Protein. Biochemistry 57:5616-5628. doi :

van Tran N, Muller L, Ross R, Lestini R, Létoquart J, Ulryck N, Limbach P, de Crécy-Lagard V, Cianférani S, Graille M. 2018. Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes. Nucleic Acids Res. 46:8483-8499. doi :

Weinsanto I, Laux-Biehlmann A, Mouheiche J, Maduna T, Delalande F, Chavant V, Gabel F, Darbon P, Charlet A, Poisbeau P, Lamshöft M, Van Dorsselaer A, Cianferani S, Parat M, Goumon Y. 2018. Stable isotope-labelled morphine to study in vivo central and peripheral morphine glucuronidation and brain transport in tolerant mice. Br J Pharmacol. 175:3844-3856. doi :

Maheul Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Chevalier-Dubois J, Diemer H, Cianférani S, Strub J, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P. 2018. The Nuclear Bile Acid Receptor FXR is a PKA- and FOXA2-Sensitive Activator of Fasting Hepatic Gluconeogenesis. Journal of Hepatology. doi :

Chopard C, Tong P, Tóth P, Schatz M, Yezid H, Debaisieux S, Mettling C, Gross A, Pugnière M, Tu A, Strub J, Mesnard J, Vitale N, Beaumelle B. 2018. Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells. Nat Commun. doi :

Garcia L, Girod M, Rompais M, Dugourd P, Carapito C, Lemoine J. 2018. Data-Independent Acquisition Coupled to Visible Laser-Induced Dissociation at 473 nm (DIA-LID) for Peptide-Centric Specific Analysis of Cysteine-Containing Peptide Subset. Anal Chem. 90:3928-3935. doi :

Bibi-Triki S, Husson G, Maucourt B, Vuilleumier S, Carapito C, Bringel F. 2018. N-terminome and proteogenomic analysis of the Methylobacterium extorquens DM4 reference strain for dichloromethane utilization. J Proteomics.:131-139. doi :

Cavallo G, Poyer S, Amalian J, Dufour F, Burel A, Carapito C, Charles L, Lutz J. 2018. Cleavable Binary Dyads : Simplifying Data Extraction and Increasing Storage Density in Digital Polymers. Angew Chem Int Ed Engl. 57:6266-6269. doi :

Ehkirch A, Hernandez-Alba O, Colas O, Beck A, Guillarme D, Cianférani S. 2018. Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products. J Chromatogr B Analyt Technol Biomed Life Sci.:176-183. doi :

Salaam J, Tabti L, Bahamyirou S, Lecointre A, Hernandez Alba O, Jeannin O, Camerel F, Cianférani S, Bentouhami E, Nonat A, Charbonnière L. 2018. Formation of Mono- and Polynuclear Luminescent Lanthanide Complexes based on the Coordination of Preorganized Phosphonated Pyridines. Inorg Chem. 57:6095-6106. doi :

Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo P, Bourguet M, Paiva A, Bragantini B, Chagot M, Robert M, Abeza C, Fabre P, Fort P, Vandermoere F, Sousa P, Rain J, Charpentier B, Cianférani S, Bandeiras T, Pradet-Balade B, Manival X, Bertrand E. 2018. The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. Nat Commun. 9:2093. doi :

Behrens C, Biela I, Petiot-Bécard S, Botzanowski T, Cianférani S, Sager C, Klebe G, Heine A, Reuter K. 2018. Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine Transglycosylase. Biochemistry. doi :

Dartevelle P, Ehlinger C, Zaet A, Boehler C, Rabineau M, Westermann B, Strub J, Cianferani S, Haïkel Y, Metz-Boutigue M, Marban C. 2018. D-Cateslytin : a new antifungal agent for the treatment of oral Candida albicans associated infections. Sci Rep. 8:9235. doi :

Ehrmann F, Kalim J, Pfaffeneder T, Bernet B, Hohn C, Schäfer E, Botzanowski T, Cianférani S, Heine A, Reuter K, Diederich F, Klebe G. 2018. Swapping Interface Contacts in the Homodimeric tRNA Guanine Transglycosylase : An Option for Functional Regulation. Angew Chem Int Ed Engl. doi :

Muller L, Fornecker L, Chion M, Van Dorsselaer A, Cianférani S, Rabilloud T, Carapito C. 2018. Extended investigation of tube-gel sample preparation : a versatile and simple choice for high throughput quantitative proteomics. Sci Rep. 8:8260. doi :

D’Atri V, Causon T, Hernandez-Alba O, Mutabazi A, Veuthey JL, Cianferani S, Guillarme D. Adding a new separation dimension to MS and LC-MS : What is the utility of ion mobility spectrometry ? J Sep Sci. 2018 Jan ;41(1):20-67. doi :

Ehkirch A, D’Atri V, Rouviere F, Hernandez-Alba O, Goyon A, Colas O, Sarrut M, Beck A, Guillarme D, Heinisch S, Cianferani S. An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates. Anal Chem. 2018 Feb 6 ;90(3):1578-1586. doi :

Grzela R, Nusbaum J, Fieulaine S, Lavecchia F, Desmadril M, Nhiri N, Van Dorsselaer A, Cianferani S, Jacquet E, Meinnel T, Giglione C. Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts. Biochim Biophys Acta. 2018 Feb ;1866(2):348-355. doi :

Husson G, Delangle A, O’Hara J, Cianferani S, Gervais A, Van Dorsselaer A, Bracewell D, Carapito C. Dual Data-Independent Acquisition Approach Combining Global HCP Profiling and Absolute Quantification of Key Impurities during Bioprocess Development. Anal Chem. 2018 Jan 16 ;90(2):1241-1247. doi :

Mori M, Kovalenko L, Malancona S, Saladini F, De Forni D, Pires M, Humbert N, Real E, Botzanowski T, Cianférani S, Giannini A, Dasso Lang MC, Cugia G, Poddesu B, Lori F, Zazzi M, Harper S, Summa V, Mely Y, Botta M. Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains. ACS Chem Biol. 2018 Jan 19 ;13(1):253-266. doi :

Dovgan I, Erb S, Hessmann S, Ursuegui S, Michel C, Muller C, Chaubet G, Cianférani S, Wagner A. Arginine-selective bioconjugation with 4-azidophenyl glyoxal : application to the single and dual functionalisation of native antibodies. Org Biomol Chem. 2018 Feb 21 ;16(8):1305-1311. doi :

Issa N, Guillaumot N, Lauret E, Matt N, Schaeffer-Reiss C, Van Dorsselaer A, Reichhart JM, Veillard F. The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway. Mol Cell. 2018 Feb 15 ;69(4):539-550.e6. doi :

Chanon S, Chazarin B, Toubhans B, Durand C, Chery I, Robert M, Vieille-Marchiset A, Swenson JE, Zedrosser A, Evans AL, Brunberg S, Arnemo JM, Gauquelin-Koch G, Storey KB, Simon C, Blanc S, Bertile F, Lefai E. Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells. Sci Rep. 2018 Apr 3 ;8(1):5525. doi :


Baxter, P. N. W., Karmazin, L., DeCian, A., Varnek, A., Gisselbrecht, J.-P., Strub, J.-M., & Cianferani, S. (2017). A Direct One-Pot Synthesis of Asymmetric Dehydrobenzopyrido-[12]annulenes and Their Physicochemical Properties. Eur. J. Org. Chem., 4625–4632. doi :

Bertile, F., Fouillen, L., Wasselin, T., Maes, P., Le Maho, Y., Van Dorsselaer, A., & Raclot, T. (2017). The Safety Limits Of An Extended Fast : Lessons from a Non-Model Organism. Sci Rep., in press, doi :

Carapito, C., Duek, P., Macron, C., Seffals, M., Rondel, K., Delalande, F., . . . Pineau, C. (2017). Validating missing proteins in human sperm cells by targeted mass spectrometry- and antibody-based methods. J Proteome Res. doi :

Charbonnel, C., Khan Niazi, A., Elvira-Matelor, E., Nowak, E., Zytnicki, M., de Bures, A., . . . Saez-Vasquez, J. (2017). The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the doublestranded-RNA-binding domain. Nucleic Acids Research, in press. doi :

D’Atri, V., Causon, T., Hernandez-Alba, O., Mutabazi, A., Veuthey, J., Cianferani, S., & Guillarme, D. (2017). Adding a new separation dimension to MS and LC-MS : What is the utility of ion mobility spectrometry ? J Sep Sci., doi :

Grillon, A., Westermann, B., Cantero, P., Jaulhac, B., Voordouw, M. J., Kapps, D., . . . Boulanger, N. (2017). Identification of Borrelia protein candidates in mouse skin for potential diagnosis of disseminated Lyme borreliosis. Scientific reports, in press.

Kolodych, S., Michel, C., Delacroix, S., Koniev, O., Ehkirch, A., Eberova, J., . . . Wagner, A. (2017). Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates. Eur J Med Chem., pii : S0223-5234(17)30611-6. doi :

Tascher, G., Brioche, T., Maes, P., Chopard, A., O’Gorman, D., Gauquelin-Koch, G., . . . Bertile, F. (2017). Proteome-wide Adaptations of Mouse Skeletal Muscles during a Full Month in Space. J. Proteome Res., 16, 2623−2638. doi :

Terral, G., CHAMPION, T., Debaene, F., Colas, O., Bourguet, M., WAGNER-ROUSSET, E., . . . Cianferani, S. (2017). Epitope characterization of anti-JAM-A antibodies using orthogonal mass spectrometry and surface plasmon resonance approaches. MAbs., doi :

Vizcaino, J. A., Walzer, M., Jimenez, R. C., Bittremieux, W., Bouyssie, D., Carapito, C., . . . Kohlbacher, O. (2017). A community proposal to integrate proteomics activities in ELIXIR. F1000Res, 6. doi :

Westermann, B., Vaca Jacome, A., Rompais, M., Carapito, C., & Schaeffer-Reiss, C. (2017). Doublet N-Terminal Oriented Proteomics for N-Terminomics and Proteolytic Processing Identification. Methods Mol Biol., 1574, 77-90. doi :

Argemi, X., Prevost, G., Riegel, P., Keller, D., Meyer, N., Baldeyrou, M., Douiri, N., Lefebvre, N., Meghit, K., Oustau, C. R., Christmann, D., Cianferani, S., Strub, J. M. & Hansmann, Y. (2017). VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis. Clinical Microbiology and Infection 23, 334.e331-334.e338. doi :

Bisse, E., Schaeffer-Reiss, C., Van Dorsselaer, A., Alayi, T. D., Epting, T., Winkler, K., Cardenas, A. S. B., Soman, J., Birukou, I., Samuel, P. P. & Olson, J. S. (2017). Hemoglobin Kirklareli (alpha H58L), a New Variant Associated with Iron Deficiency and Increased CO Binding. J. Biol. Chem. 292, 2542-2555. doi :

Botzanowski, T., Erb, S., Hernandez-Alba, O., Ehkirch, A., Colas, O., Wagner-Rousset, E., Rabuka, D., Beck, A., Drake, P. M. & Cianferani, S. (2017). Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates. Mabs 9, 801-811. doi :

Bourgeois, G., Marcoux, J., Saliou, J. M., Cianferani, S. & Graille, M. (2017). Activation mode of the eukaryotic m(2)G(10) tRNA methyltransferase Trm11 by its partner protein Trm112. Nucleic Acids Res. 45, 1971-1982. doi :

Burel, A., Carapito, C., Lutz, J. F. & Charles, L. (2017). MS-DECODER : Milliseconds Sequencing of Coded Polymers. Macromolecules 50, 8290-8296. doi :

Carapito, C., Kuhn, L., Karim, L., Rompais, M., Rabilloud, T., Schwenzer, H. & Sissler, M. (2017). Two proteomic methodologies for defining N-termini of mature human mitochondrial aminoacyl-tRNA synthetases. Methods 113, 111-119. doi :

Cura, V., Marechal, N., Troffer-Charlier, N., Strub, J. M., Van Haren, M. J., Martin, N. I., Cianferani, S., Bonnefond, L. & Cavarelli, J. (2017). Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. Febs Journal 284, 77-96. doi :

Dalzon, B., Aude-Garcia, C., Collin-Faure, V., Diemer, H., Beal, D., Dussert, F., Fenel, D., Schoehn, G., Cianferani, S., Carriere, M. & Rabilloud, T. (2017). Differential proteomics highlights macrophage-specific responses to amorphous silica nanoparticles. Nanoscale 9, 9641-9658. doi :

Dovgan, I., Ursuegui, S., Erb, S., Miche, C., Kolodych, S., Cianferani, S. & Wagner, A. (2017). Acyl Fluorides : Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy. Bioconjugate Chem. 28, 1452-1457. doi :

Ehrmann, F. R., Stojko, J., Metz, A., Debaene, F., Barandun, L. J., Heine, A., Diederich, F., Cianferani, S., Reuter, K. & Klebe, G. (2017). Soaking suggests " alternative facts " : Only cocrystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition. Plos One 12, e0175723. doi :

Gissot, M., Hovasse, A., Chaloin, L., Schaeffer-Reiss, C., Van Dorsselaer, A. & Tomavo, S. (2017). An evolutionary conserved zinc finger protein is involved in Toxoplasma gondii mRNA nuclear export. Cellular Microbiology 19, e12644. doi :

Guegueniat, J., Dupin, A. F., Stojko, J., Beaurepaire, L., Cianferani, S., Mackereth, C. D., Minvielle-Sebastia, L. & Fribourg, S. (2017). Distinct roles of Pcf11 zinc-binding domains in pre-mRNA3 ’-end processing. Nucleic Acids Res. 45, 10115-10131. doi :

Kadek, A., Kavan, D., Marcoux, J., Stojko, J., Felice, A. K. G., Cianferani, S., Ludwig, R., Halada, P. & Man, P. (2017). Interdomain electron transfer in cellobiose dehydrogenase is governed by surface electrostatics. Biochimica Et Biophysica Acta-General Subjects 1861, 157-167. doi :

Lanshoeft, C., Cianferani, S. & Heudi, O. (2017). Generic Hybrid Ligand Binding Assay Liquid Chromatography High Resolution Mass Spectrometry-Based Workflow for Multiplexed Human Immunoglobulin G1 Quantification at the Intact Protein Level : Application to Preclinical Pharmacokinetic Studies. Anal. Chem. 89, 2628-2635. doi :

Lemaitre-Guillier, C., Hovasse, A., Schaeffer-Reiss, C., Recorbet, G., Poinssot, B., Trouvelot, S., Daire, X., Adrian, M. & Heloir, M. C. (2017). Proteomics towards the understanding of elicitor induced resistance of grapevine against downy mildew. J. Proteom. 156, 113-125. doi :

Licona, C., Spaety, M. E., Capuozzo, A., Ali, M., Santamaria, R., Armant, O., Delalande, F., Van Dorsselaer, A., Cianferani, S., Spencer, J., Pfeffer, M., Mellitzer, G. & Gaiddon, C. (2017). A ruthenium anticancer compound interacts with histones and impacts differently on epigenetic and death pathways compared to cisplatin. Oncotarget 8, 2568-2584. doi :

Mohideen-Abdul, K., Tazibt, K., Bourguet, M., Hazemann, I., Lebars, I., Takacs, M., Cianferani, S., Klaholz, B. P., Moras, D. & Billas, I. M. L. (2017). Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor. Frontiers in Endocrinology 8, 140. doi :

Montacie, C., Durut, N., Opsomer, A., Palm, D., Comella, P., Picart, C., Carpentier, M. C., Pontvianne, F., Carapito, C., Schleiff, E. & Saez-Vasquez, J. (2017). Nucleolar Proteome Analysis and Proteasomal Activity Assays Reveal a Link between Nucleolus and 26S Proteasome in A. thaliana. Frontiers in Plant Science 8, 13. doi :

Paleari, R., Caruso, D., Kaiser, P., Arsene, C. G., Schaeffer-Reiss, C., Van Dorsselaer, A., Bisse, E., Ospina, M., De Jesus, V. R., Wild, B., Mosca, A. & Standardisation, I. W. G. (2017). Developing a reference system for the IFCC standardization of HbA(2). Clin. Chim. Acta 467, 21-26. doi :

Radu, L., Schoenwetter, E., Braun, C., Marcoux, J., Koelmel, W., Schmitt, D. R., Kuper, J., Cianferani, S., Egly, J. M., Poterszman, A. & Kisker, C. (2017). The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH. Nucleic Acids Res. 45, 10872-10883. doi :

Roux, A., Gillet, R., Huclier-Markai, S., Ehret-Sabatier, L., Charbonniere, L. J. & Nonat, A. M. (2017). Bifunctional bispidine derivatives for copper-64 labelling and positron emission tomography. Org. Biomol. Chem. 15, 1475-1483. doi :

Stojko, J., Dupin, A., Chaignepain, S., Beaurepaire, L., Vallet-Courbin, A., Van Dorsselaer, A., Schmitter, J. M., Minvielle-Sebastia, L., Fribourg, S. & Cianferani, S. (2017). Structural characterization of the yeast CF IA complex through a combination of mass spectrometry approaches. Int. J. Mass spectrom. 420, 57-66. doi :

Wagner-Rousset, E., Fekete, S., Morel-Chevillet, L., Colas, O., Corvaia, N., Cianferani, S., Guillarme, D. & Beck, A. (2017). Development of a fast workflow to screen the charge variants of therapeutic antibodies. J. Chromatogr. A 1498, 147-154. doi :


Armand, L., Biola-Clier, M., Bobyk, L., Collin-Faure, V., Diemer, H., Strub, J. M., Cianferani, S., Van Dorsselaer, A., Herlin-Boime, N., Rabilloud, T. & Carriere, M. (2016). Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles : A proteomic view. J. Proteom. 134, 163-173. doi :

Aude-Garcia, C., Dalzon, B., Ravanat, J. L., Collin-Faure, V., Diemer, H., Strub, J. M., Cianferani, S., Van Dorsselaer, A., Carriere, M. & Rabilloud, T. (2016). A combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages. J. Proteom. 134, 174-185. doi :

Beck, A., Terral, G., Debaene, F., Wagner-Rousset, E., Marcoux, J., Janin-Bussat, M. C., Colas, O., Van Dorsselaer, A. & Cianferani, S. (2016). Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates. Expert Review of Proteomics 13, 157-183. doi :

Bragantini, B., Tiotiu, D., Rothe, B., Saliou, J. M., Marty, H., Cianferani, S., Charpentier, B., Quinternet, M. & Manival, X. (2016). Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis. J. Mol. Biol. 428, 2488-2506. doi :

Hovasse, A., Alayi, T. D., Van Dorsselaer, A., Marchal, R., Jegou, S. & Schaeffer-Reiss, C. (2016). In-depth glycoproteomic characterisation of grape berry vacuolar invertase using a combination of mass spectrometry-based approaches. Food Chem. 200, 237-244. doi :

Lanshoeft, C., Heudi, O. & Cianferani, S. (2016). SMART Digest (TM) compared with pellet digestion for analysis of human immunoglobulin G1 in rat serum by liquid chromatography tandem mass spectrometry. Anal. Biochem. 501, 23-25. doi :

Lanshoeft, C., Heudi, O., Cianferani, S., Warren, A. P., Picard, F. & Kretz, O. (2016). Quantitative analysis of hIgG1 in monkey serum by LC-MS/MS using mass spectrometric immunoassay. Bioanalysis 8, 1035-1049. doi :

Lanshoeft, C., Wolf, T., Heudi, O., Cianferani, S., Barteau, S., Walles, M., Picard, F. & Kretz, O. (2016). The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry. Anal. Bioanal. Chem. 408, 1687-1699. doi :

Lederer, M., Hahn, U., Strub, J. M., Cianferani, S., Van Dorsselaer, A., Nierengarten, J. F., Torres, T. & Guldi, D. M. (2016). Probing Supramolecular Interactions between a Crown Ether Appended Zinc Phthalocyanine and an Ammonium Group Appended to a C-60 Derivative. Chem. Eur. J. 22, 2051-2059. doi :

Luche, S., Eymard-Vernain, E., Diemer, H., Van Dorsselaer, A., Rabilloud, T. & Lelong, C. (2016). Zinc oxide induces the stringent response and major reorientations in the central metabolism of Bacillus subtilis. J. Proteom. 135, 170-180. doi :

Plumel, M. I., Benhaim-Delarbre, M., Rompais, M., Thiersé, D., Sorci, G., Van Dorsselaer, A., Criscuolo, F. & Bertile, F. (2016). Differential proteomics reveals age-dependent liver oxidative costs of innate immune activation in mice. J. Proteom. 135, 181-190. doi :

Ramus, C., Hovasse, A., Marcellin, M., Hesse, A. M., Mouton-Barbosa, E., Bouyssie, D., Vaca, S., Carapito, C., Chaoui, K., Bruley, C., Garin, J., Cianferani, S., Ferro, M., Van Dorssaeler, A., Burlet-Schiltz, O., Schaeffer, C., Coute, Y. & De Peredo, A. G. (2016). Benchmarking quantitative label-free LC-MS data processing workflows using a complex spiked proteomic standard dataset. J. Proteom. 132, 51-62. doi :

Sangare, L. O., Alayi, T. D., Westermann, B., Hovasse, A., Sindikubwabo, F., Callebaut, I., Werkmeister, E., Lafont, F., Slomianny, C., Hakimi, M. A., Van Dorsselaer, A., Schaeffer-Reiss, C. & Tomavo, S. (2016). Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection. Nat. Commun. 7, 11191. doi :

Sigwalt, D., Caballero, R., Holler, M., Strub, J. M., Van Dorsselaer, A. & Nierengarten, J. F. (2016). Ultra-Fast Dendritic Growth Based on the Grafting of Fullerene Hexa-Adduct Macromonomers onto a Fullerene Core. Eur. J. Org. Chem., 2882-2887. doi :

Soty, M., Chilloux, J., Delalande, F., Zitoun, C., Bertile, F., Mithieux, G. & Gautier-Stein, A. (2016). Post-Translational Regulation of the Glucose-6-Phosphatase Complex by Cyclic Adenosine Monophosphate Is a Crucial Determinant of Endogenous Glucose Production and Is Controlled by the Glucose-6-Phosphate Transporter. J. Proteom. Res. 15, 1342-1349. doi :

Thebault, S., Agez, M., Chi, X. K., Stojko, J., Cura, V., Telerman, S. B., Maillet, L., Gautier, F., Billas-Massobrio, I., Birck, C., Troffer-Charlier, N., Karafin, T., Honore, J., Senff-Ribeiro, A., Montessuit, S., Johnson, C. M., Juin, P., Cianferani, S., Martinou, J. C., Andrews, D. W., Amson, R., Telerman, A. & Cavarelli, J. (2016). TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL. Sci. Rep. 6, 19725. doi :

Vandenbrouck, Y., Lane, L., Carapito, C., Duek, P., Rondel, K., Bruley, C., Macron, C., Gonzalez de Peredo, A., Coute, Y., Chaoui, K., Com, E., Gateau, A., Hesse, A.M., Marcellin, M., Mear, L., Mouton-Barbosa, E., Robin, T., Burlet-Schiltz, O., Cianferani, S., Ferro, M., Freour, T., Lindskog, C., Garin, J., and Pineau, C. (2016) Looking for Missing Proteins in the Proteome of Human Spermatozoa : An Update, J Proteome Res 15(11), 3998-4019. doi :

Ramus, C., Hovasse, A., Marcellin, M., Hesse, A.M., Mouton-Barbosa, E., Bouyssie, D., Vaca, S., Carapito, C., Chaoui, K., Bruley, C., Garin, J., Cianferani, S., Ferro, M., Dorssaeler, A.V., Burlet-Schiltz, O., Schaeffer, C., Coute, Y., and Gonzalez de Peredo, A. (2016) Spiked proteomic standard dataset for testing label-free quantitative software and statistical methods, Data Brief 6, 286-94. doi :

Muller, L., Fornecker, L., Van Dorsselaer, A., Cianferani, S., and Carapito, C. (2016) Benchmarking sample preparation/digestion protocols reveals tube-gel being a fast and repeatable method for quantitative proteomics, Proteomics 16(23), 2953-2961. doi :

Kusebauch, U., Campbell, D.S., Deutsch, E.W., Chu, C.S., Spicer, D.A., Brusniak, M.Y., Slagel, J., Sun, Z., Stevens, J., Grimes, B., Shteynberg, D., Hoopmann, M.R., Blattmann, P., Ratushny, A.V., Rinner, O., Picotti, P., Carapito, C., Huang, C.Y., Kapousouz, M., Lam, H., Tran, T., Demir, E., Aitchison, J.D., Sander, C., Hood, L., Aebersold, R., and Moritz, R.L. (2016) Human SRMAtlas : A Resource of Targeted Assays to Quantify the Complete Human Proteome, Cell 166, 1-13. doi :

Hovasse, A., Bruneel, O., Casiot, C., Desoeuvre, A., Farasin, J., Hery, M., Van Dorsselaer, A., Carapito, C., and Arsene-Ploetze, F. (2016) Spatio-Temporal Detection of the Thiomonas Population and the Thiomonas Arsenite Oxidase Involved in Natural Arsenite Attenuation Processes in the Carnoules Acid Mine Drainage, Front Cell Dev Biol 4, 3. doi :

Frottin, F., Bienvenut, W., Bignon, J., Jacquet, E., Vaca Jacome, A.S., Van Dorssaeler, A., Cianferani, S., Carapito, C., Meinnel, T., and Giglione, C. (2016) MetAP1 and MetAP2 drive cell selectivity for a potent anticancer agent in synergy, by controlling glutathione redox state, Oncotarget, in press. doi :

Carapito, C., Kuhn, L., Karim, L., Rompais, M., Rabilloud, T., Schwenzer, H., and Sissler, M. (2016) Two proteomic methodologies for defining N-termini of mature human mitochondrial aminoacyl-tRNA synthetases, Methods, in press. doi :


Ait-Ali, N., Fridlich, R., Millet-Puel, G., Clerin, E., Delalande, F., Jaillard, C., Blond, F., Perrocheau, L., Reichman, S., Byrne, L. C., Olivier-Bandini, A., Bellalou, J., Moyse, E., Bouillaud, F., Nicol, X., Dalkara, D., Van Dorsselaer, A., Sahel, J. A. & Leveillard, T. (2015). Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis. Cell 161, 817-832. doi :

Arsene-Ploetze, F., Bertin, P. N. & Carapito, C. (2015). Proteomic tools to decipher microbial community structure and functioning. Environ. Sci. Pollution Res. 22, 13599-13612. doi :

Ayoub, D., Bertaccini, D., Diemer, H., Wagner-Rousset, E., Colas, O., Cianferani, S., Van Dorsselaer, A., Beck, A. & Schaeffer-Reiss, C. (2015). Characterization of the N-Terminal Heterogeneities of Monoclonal Antibodies Using In-Gel Charge Derivatization of alpha-Amines and LC-MS/MS. Anal. Chem. 87, 3784-3790. doi :

Beck, A., Debaene, F., Diemer, H., Wagner-Rousset, E., Colas, O., Van Dorsselaer, A. & Cianferani, S. (2015). Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies. J. Mass Spectrom. 50, 285-297. doi :

Bonnefond, L., Stojko, J., Mailliot, J., Troffer-Charlier, N., Cura, V., Wurtz, J. M., Cianferani, S. & Cavarelli, J. (2015). Functional insights from high resolution structures of mouse protein arginine methyltransferase 6. J. Struct. Biol. 191, 175-183. doi :

Carapito, C., Lane, L., Benama, M., Opsomer, A., Mouton-Barbosa, E., Garrigues, L., De Peredo, A. G., Burel, A., Bruley, C., Gateau, A., Bouyssie, D., Jaquinod, M., Cianferani, S., Burlet-Schiltz, O., Van Dorsselaer, A., Garin, J. & Vandenbrouck, Y. (2015). Computational and Mass-Spectrometry-Based Workflow for the Discovery and Validation of Missing Human Proteins : Application to Chromosomes 2 and 14. J. Proteom. Res. 14, 3621-3634. doi :

Dorier, M., Brun, E., Veronesi, G., Barreau, F., Pernet-Gallay, K., Desvergne, C., Rabilloud, T., Carapito, C., Herlin-Boime, N. & Carriere, M. (2015). Impact of anatase and rutile titanium dioxide nanoparticles on uptake carriers and efflux pumps in Caco-2 gut epithelial cells. Nanoscale 7, 7352-7360. doi :

Ethuin, P., Marlard, S., Delosiere, M., Carapito, C., Delalande, F., Van Dorsselaer, A., Dehaut, A., Lencel, V., Duflos, G. & Grard, T. (2015). Differentiation between fresh and frozen-thawed sea bass (Dicentrarchus labrax) fillets using two-dimensional gel electrophoresis. Food Chem. 176, 294-301. doi :

Jakobi, S., Nguyen, P. T. X., Debaene, F., Cianferani, S., Reuter, K. & Klebe, G. (2015). What Glues a Homodimer Together : Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme Tgt. ACS Chem. Biol. 10, 1897-1907. doi :

Kern, A., Schnell, G., Bernard, Q., Boeuf, A., Jaulhac, B., Collin, E., Barthel, C., Ehret-Sabatier, L. & Boulanger, N. (2015). Heterogeneity of Borrelia burgdorferi Sensu Stricto Population and Its Involvement in Borrelia Pathogenicity : Study on Murine Model with Specific Emphasis on the Skin Interface. Plos One 10, e0133195. doi :

Kolodych, S., Koniev, O., Baatarkhuu, Z., Bonnefoy, J.-Y., Debaene, F., Cianferani, S., Van Dorsselaer, A. & Wagner, A. (2015). CBTF : New Amine-to-Thiol Coupling Reagent for Preparation of Antibody Conjugates with Increased Plasma Stability. Bioconjugate Chem. 26, 197-200. doi :

Koniev, O., Kolodych, S., Baatarkhuu, Z., Stojko, J., Eberova, J., Bonnefoy, J. Y., Cianferani, S., Van Dorsselaer, A. & Wagner, A. (2015). MAPN : First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation. Bioconjugate Chem. 26, 1863-1867. doi :

Leveillard, T., Van Dorsselaer, A. & Sahel, J. A. (2015). Altruism in the retina : sticks feed cones. M S-Med. Sci. 31, 828-830. doi :

Marcoux, J., Champion, T., Colas, O., Wagner-Rousset, E., Corvaia, N., Van Dorsselaer, A., Beck, A. & Cianferani, S. (2015). Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate. Protein Sci. 24, 1210-1223. doi :

Marcoux, J. & Cianferani, S. (2015). Towards integrative structural mass spectrometry : Benefits from hybrid approaches. Methods 89, 4-12. doi :

Marcoux, J., Mangione, P. P., Porcari, R., Degiacomi, M. T., Verona, G., Taylor, G. W., Giorgetti, S., Raimondi, S., Sanglier-Cianferani, S., Benesch, J. L. P., Cecconi, C., Naqvi, M. M., Gillmore, J. D., Hawkins, P. N., Stoppini, M., Robinson, C. V., Pepys, M. B. & Bellotti, V. (2015). A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis. EMBO Mol. Med. 7, 1337-1349. doi :

Martin, P., Dubois, C., Jacquier, E., Dion, S., Mancini-Bourgine, M., Godon, O., Kratzer, R., Lelu-Santolaria, K., Evlachev, A., Meritet, J. F., Schlesinger, Y., Villeval, D., Strub, J. M., Van Dorsselaer, A., Marchand, J. B., Geist, M., Brandely, R., Findeli, A., Boukhebza, H., Menguy, T., Silvestre, N., Michel, M. L. & Inchauspe, G. (2015). TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice. Gut 64, 1961-1971. doi :

Martinez-Zapien, D., Saliou, J. M., Han, X., Atmanene, C., Proux, F., Cianferani, S. & Dock-Bregeon, A. C. (2015). Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective. Biochimie 117, 63-71. doi :

Quinternet, M., Rothe, B., Barbier, M., Bobo, C., Saliou, J. M., Jacquemin, C., Back, R., Chagot, M. E., Cianferani, S., Meyer, P., Branlant, C., Charpentier, B. & Manival, X. (2015). Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly. J. Mol. Biol. 427, 2816-2839. doi :

Saliou, J. M., Manival, X., Tillault, A. S., Atmanene, C., Bobo, C., Branlant, C., Van Dorsselaer, A., Charpentier, B. & Cianferani, S. (2015). Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity. Proteomics 15, 2851-2861. doi :

Schnell, G., Boeuf, A., Jaulhac, B., Boulanger, N., Collin, E., Barthel, C., De Martino, S. & Ehret-Sabatier, L. (2015). Proteomic analysis of three Borrelia burgdorferi sensu lato native species and disseminating clones : Relevance for Lyme vaccine design. Proteomics 15, 1280-1290. doi :

Schnell, G., Boeuf, A., Westermann, B., Jaulhac, B., Lipsker, D., Carapito, C., Boulanger, N. & Ehret-Sabatier, L. (2015). Discovery and Targeted Proteomics on Cutaneous Biopsies Infected by Borrelia to Investigate Lyme Disease. Mol. Cell. Proteomics 14, 1254-1264. doi :

Simonneau, C., Leclercq, B., Mougel, A., Adriaenssens, E., Paquet, C., Raibaut, L., Ollivier, N., Drobecq, H., Marcoux, J., Cianferani, S., Tulasne, D., De Jonge, H., Melnyk, O. & Vicogne, J. (2015). Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist. Chem. Sci. 6, 2110-2121. doi :

Stojko, J., Fieulaine, S., Petiot-Becard, S., Van Dorsselaer, A., Meinnel, T., Giglione, C. & Cianferani, S. (2015). Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes. Analyst 140, 7234-7245. doi :

Triboulet, S., Aude-Garcia, C., Armand, L., Collin-Faure, V., Chevallet, M., Diemer, H., Gerdil, A., Proamer, F., Strub, J. M., Habert, A., Herlin, N., Van Dorsselaer, A., Carriere, M. & Rabilloud, T. (2015). Comparative Proteomic Analysis of the Molecular Responses of Mouse Macrophages to Titanium Dioxide and Copper Oxide Nanoparticles Unravels Some Toxic Mechanisms for Copper Oxide Nanoparticles in Macrophages. Plos One 10, e0124496. doi :

Vaca Jacome, A. S., Rabilloud, T., Schaeffer-Reiss, C., Rompais, M., Ayoub, D., Lane, L., Bairoch, A., Van Dorsselaer, A. & Carapito, C. (2015). N-terminome analysis of the human mitochondrial proteome. Proteomics 15, 2519-2524. doi :


Abada, S., Lecointre, A., Christine, C., Ehret-Sabatier, L., Saupe, F., Orend, G., Brasse, D., Ouadi, A., Hussenet, T., Laquerrière, P., Elhabiri, M. & Charbonnière, L. J. (2014). Phosphonated Chelates for Nuclear Imaging. Org. Biomol. Chem. 12, 9601-9620. doi :

Alayi, T. D., Van Dorsselaer, A., Epting, T., Bisse, E. & Schaeffer-Reiss, C. (2014). Hb A(2)-Konz delta 50(D1)Ser -> Thr ; HBD : c.151T > A : a New delta Chain Hemoglobin Variant Characterized by Mass Spectrometry and High Performance Liquid Chromatography. Hemoglobin 38, 133-136. doi :

Brun, E., Barreau, F., Veronesi, G., Fayard, B., Sorieul, S., Chaneac, C., Carapito, C., Rabilloud, T., Mabondzo, A., Herlin-Boime, N. & Carriere, M. (2014). Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia. Part. Fibre Toxicol. 11, 13. doi :

Carapito, C., Burel, A., Guterl, P., Walter, A., Varrier, F., Bertile, F. & Van Dorsselaer, A. (2014). MSDA, a proteomics software suite for in-depth Mass Spectrometry Data Analysis using grid computing. Proteomics 14, 1014-1019. doi :

Cebron, A., Arsene-Ploetze, F., Bauda, P., Bertin, P. N., Billard, P., Carapito, C., Devin, S., Goulhen-Chollet, F., Poirel, J. & Leyval, C. (2014). Rapid Impact of Phenanthrene and Arsenic on Bacterial Community Structure and Activities in Sand Batches. Microb. Ecol. 67, 129-144. doi :

Cotte, V., Sabatier, L., Schnell, G., Carmi-Leroy, A., Rousselle, J. C., Arsene-Ploetze, F., Malandrin, L., Sertour, N., Namane, A., Ferquel, E. & Choumet, V. (2014). Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex. J. Proteom. 96, 29-43. doi :

Debaene, F., Boeuf, A., Wagner-Rousset, E., Colas, O., Ayoub, D., Corvaia, N., Van Dorsselaer, A., Beck, A. & Cianferani, S. (2014). Innovative Native MS Methodologies for Antibody Drug Conjugate Characterization : High Resolution Native MS and IM-MS for Average DAR and DAR Distribution Assessment. Anal. Chem. 86, 10674-10683. doi :

Debeire, P., Delalande, F., Habrylo, O., Jeltsch, J. M., Van Dorsselaer, A. & Phalip, V. (2014). Enzymatic cocktails produced by Fusarium graminearum under submerged fermentation using different lignocellulosic biomasses. FEMS Microbiol. Lett. 355, 116-123. doi :

Feve, M., Saliou, J. M., Zeniou, M., Lennon, S., Carapito, C., Dong, J. H., Van Dorsselaer, A., Junier, M. P., Chneiweiss, H., Cianferani, S., Haiech, J. & Kilhoffer, M. C. (2014). Comparative Expression Study of the Endo-G Protein Coupled Receptor (GPCR) Repertoire in Human Glioblastoma Cancer Stem-like Cells, U87-MG Cells and Non Malignant Cells of Neural Origin Unveils New Potential Therapeutic Targets. Plos One 9, e91519. doi :

Herissant, L., Moehle, E. A., Bertaccini, D., Van Dorsselaer, A., Schaeffer-Reiss, C., Guthrie, C. & Dargemont, C. (2014). H2B ubiquitylation modulates spliceosome assembly and function in budding yeast. Biol. Cell 106, 126-138. doi :

Jakobi, S., Nguyen, T. X. P., Debaene, F., Metz, A., Sanglier-Cianferani, S., Reuter, K. & Klebe, G. (2014). Hot-spot analysis to dissect the functional protein-protein interface of a tRNA-modifying enzyme. Proteins 82, 2713-2732. doi :

Jemaa, M., Morin, N., Cavelier, P., Cau, J., Strub, J. M. & Delsert, C. (2014). Adult somatic progenitor cells and hematopoiesis in oysters. J. Exp. Biol. 217, 3067-3077. doi :

Juste, C., Kreil, D. P., Beauvallet, C., Guillot, A., Vaca, S., Carapito, C., Mondot, S., Sykacek, P., Sokol, H., Blon, F., Lepercq, P., Levenez, F., Valot, B., Carre, W., Loux, V., Pons, N., David, O., Schaeffer, B., Lepage, P., Martin, P., Monnet, V., Seksik, P., Beaugerie, L., Ehrlich, S. D., Gibrat, J. F., Van Dorsselaer, A. & Dore, J. (2014). Bacterial protein signals are associated with Crohn’s disease. Gut 63, 1566-1577. doi :

Koniev, O., Leriche, G., Nothisen, M., Remy, J. S., Strub, J. M., Schaeffer-Reiss, C., Van Dorsselaer, A., Baati, R. & Wagner, A. (2014). Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles. Bioconjugate Chem. 25, 202-206. doi :

Laux-Biehlmann, A., Chung, H., Mouheiche, J., Veriepe, J., Delalande, F., Lamshoft, M., Welters, I. D., Soldevila, S., Bazin, H., Lamarque, L., Van Dorsselaer, A., Poisbeau, P., Schneider, F., Goumon, Y. & Garnero, P. (2014). Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients : Validation of a specific anti-M6G antibody for clinical and basic research. Biofactors 40, 113-120. doi :

Leveillard, T., Fridlich, R., Clerin, E., Ait-Ali, N., Millet-Puel, G., Jaillard, C., Yang, Y., Zack, D., Van Dorsselaer, A. & Sahel, J.-A. (2014). Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors. C. R. Biol. 337, 207-213. doi :

Lien, F., Berthier, A., Bouchaert, E., Gheeraert, C., Alexandre, J., Porez, G., Prawitt, J., Dehondt, H., Ploton, M., Colin, S., Lucas, A., Patrice, A., Pattou, F., Diemer, H., Van Dorsselaer, A., Rachez, C., Kamilic, J., Groen, A. K., Staels, B. & Lefebvre, P. (2014). Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk. J. Clin. Invest. 124, 1037-1051. doi :

Liu, T., Nonat, A., Beyler, M., Regueiro-Figueroa, M., Nono, K. N., Jeannin, O., Camerel, F., Debaene, F., Cianferani-Sanglier, S., Tripier, R., Platas-Iglesias, C. & Charbonniere, L. J. (2014). Supramolecular Luminescent Lanthanide Dimers for Fluoride Sequestering and Sensing. Angew. Chem. Int. Ed. 53, 7259-7263. doi :

Magnin-Robert, M., Spagnolo, A., Alayi, T. D., Cilindre, C., Mercier, L., Schaeffer-Reiss, C., Van Dorsselaer, A., Clement, C. & Fontaine, F. (2014). Proteomic insights into changes in grapevine wood in response to esca proper and apoplexy. Phytopathol. Mediterr. 53, 168-187. doi :

Moog, C., Dereuddre-Bosquet, N., Teillaud, J. L., Biedma, M. E., Holl, V., Van Ham, G., Heyndrickx, L., Van Dorsselaer, A., Katinger, D., Vcelar, B., Zolla-Pazner, S., Mangeot, I., Kelly, C., Shattock, R. J. & Le Grand, R. (2014). Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques. Mucosal Immunol. 7, 46-56. doi :

Mori, M., Nucci, A., Chiara, M., Lang, D. S., Humbert, N., Boudier, C., Debaene, F., Sanglier-Cianferani, S., Catala, M., Schult-Dietrich, P., Dietrich, U., Tisne, C., Mely, Y. & Botta, M. (2014). Functional and Structural Characterization of 2-Amino-4-phenylthiazole Inhibitors of the HIV-1 Nucleocapsid Protein with Antiviral Activity. ACS Chem. Biol. 9, 1950-1955. doi :

Plumel, M. I., Stier, A., Thiercé, D., Van Dorsselaer, A., Criscuolo, F. & Bertile, F. (2014). Litter size manipulation in laboratory mice : an example of how proteomic analysis can uncover new mechanisms underlying the cost of reproduction. Front. Zool. 11, 41. doi :

Ranaei-Siadat, E., Merigoux, C., Seijo, B., Ponchon, L., Saliou, J. M., Bernauer, J., Sanglier-Cianferani, S., Dardel, F., Vachette, P. & Nonin-Lecomte, S. (2014). In vivo tmRNA protection by SmpB and pre-ribosome binding conformation in solution. RNA-A PUBLICATION OF THE RNA SOCIETY 20, 1827-1827. doi :

Rejon, J. D., Delalande, F., Schaeffer-Reiss, C., Carapito, C., Zienkiewicz, K., De Dios Alche, J., Isabel Rodriguez-Garcia, M., Van Dorsselaer, A. & Castro, A. J. (2014). The plant stigma exudate : a biochemically active extracellular environment for pollen germination ? Plant Sign. Behav. 9, e28274. doi :

Rothe, B., Saliou, J. M., Quinternet, M., Back, R., Tiotiu, D., Jacquemin, C., Loegler, C., Schlotter, F., Pena, V., Eckert, K., Morera, S., Van Dorsselaer, A., Branlant, C., Massenet, S., Sanglier-Cianferani, S., Manival, X. & Charpentier, B. (2014). Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction. Nucleic Acids Res. 42, 10731-10747. doi :

Spagnolo, A., Larignon, P., Magnin-Robert, M., Hovasse, A., Cilindre, C., Van Dorsselaer, A., Clement, C., Schaeffer-Reiss, C. & Fontaine, F. (2014). Flowering as the Most Highly Sensitive Period of Grapevine (Vitis vinifera L. cv Mourvedre) to the Botryosphaeria Dieback Agents Neofusicoccum parvum and Diplodia seriata Infection. Int. J. Mol. Sci. 15, 9644-9669. doi :

Spagnolo, A., Magnin-Robert, M., Alayi, T. D., Cilindre, C., Schaeffer-Reiss, C., Van Dorsselaer, A., Clement, C., Larignon, P., Ramirez-Suero, M., Chong, J., Bertsch, C., Abou-Mansour, E. & Fontaine, F. (2014). Differential Responses of Three Grapevine Cultivars to Botryosphaeria Dieback. Phytopathology 104, 1021-1035. doi :

Triboulet, S., Aude-Garcia, C., Armand, L., Gerdil, A., Diemer, H., Proamer, F., Collin-Faure, V., Habert, A., Strub, J. M., Hanau, D., Herlin, N., Carriere, M., Van Dorsselaer, A. & Rabilloud, T. (2014). Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles : a combined targeted and proteomic approach. Nanoscale 6, 6102-6114. doi :

Voinot, F., Fischer, C., Schmitt, C., Ehret-Sabatier, L. & Angel, F. (2014). Controlled ingestion of kaolinite (5%) modulates enteric nitrergic innervation in rats. Fundam. Clin. Pharmacol. 28, 405-413. doi :

Wasselin, T., Zahn, S., Le Maho, Y., Van Dorsselaer, A., Raclot, T. & Bertile, F. (2014). Exacerbated oxidative stress in the fasting liver according to fuel partitioning. Proteomics 14, 1905-1921. doi :


Aslam, R., Laventie, B. J., Marban, C., Prevost, G., Keller, D., Strub, J. M., Van Dorsselaer, A., Haikel, Y., Taddei, C. & Metz-Boutigue, M. H. (2013). Activation of Neutrophils by the Two-Component Leukotoxin LukE/D from Staphylococcus aureus : Proteomic Analysis of the Secretions. J. Proteom. Res. 12, 3667-3678. doi :

Aslam, R., Marban, C., Corazzol, C., Jehl, F., Delalande, F., Van Dorsselaer, A., Prevost, G., Haikel, Y., Taddei, C., Schneider, F. & Metz-Boutigue, M. H. (2013). Cateslytin, a Chromogranin A Derived Peptide Is Active against Staphylococcus aureus and Resistant to Degradation by Its Proteases. Plos One 8, e68993. doi :

Atindehou, M., Lagnika, L., Guérold, B., Strub, J., Marchioni, E., Zhao, M., Van Dorsselaer, A., Haikel, Y., Sanni, A. & Metz-Boutigue, M. (2013). Isolation and Identification of Two Antibacterial Agents from Chromolaena odorata L. Active against Four Diarrheal Strains. Adv. Microbiol. 3, 115-121. doi :

Beck, A., Diemer, H., Ayoub, D., Debaene, F., Wagner-Rousset, E., Carapito, C., Van Dorsselaer, A. & Sanglier-Cianferani, S. (2013). Analytical characterization of biosimilar antibodies and Fc-fusion proteins. TRAC 48, 81-95. doi :

Beck, A., Wagner-Rousset, E., Ayoub, D., Van Dorsselaer, A. & Sanglier-Cianferani, S. (2013). Characterization of Therapeutic Antibodies and Related Products. Anal. Chem. 85, 715-736. doi :

Bertaccini, D., Vaca, S., Carapito, C., Arsene-Ploetze, F., Van Dorsselaer, A. & Schaeffer-Reiss, C. (2013). An Improved Stable Isotope N-Terminal Labeling Approach with Light/Heavy TMPP To Automate Proteogenomics Data Validation : dN-TOP. J. Proteom. Res. 12, 3063-3070. doi :

Debaene, F., Wagner-Rousset, E., Colas, O., Ayoub, D., Corvaia, N., Van Dorsselaer, A., Beck, A. & Cianferani, S. (2013). Time Resolved Native Ion-Mobility Mass Spectrometry to Monitor Dynamics of IgG4 Fab Arm Exchange and "Bispecific" Monoclonal Antibody Formation. Anal. Chem. 85, 9785-9792. doi :

Gillet, F. X., Cattoni, D. I., Petiot-Becard, S., Delalande, F., Poignavent, V., Brizard, J. P., Bessin, Y., Van Dorsselaer, A., Declerck, N., Sanglier-Cianferani, S., Brugidou, C. & Vignols, F. (2013). The RYMV-Encoded Viral Suppressor of RNA Silencing P1 Is a Zinc-Binding Protein with Redox-Dependent Flexibility. J. Mol. Biol. 425, 2423-2435. doi :

Gissot, M., Walker, R., Delhaye, S., Alayi, T. D., Huot, L., Hot, D., Callebaut, I., Schaeffer-Reiss, C., Van Dorsselaer, A. & Tomavo, S. (2013). Toxoplasma gondii Alba Proteins Are Involved in Translational Control of Gene Expression. J. Mol. Biol. 425, 1287-1301. doi :

Immekus, F., Barandun, L. J., Betz, M., Debaene, F., Petiot, S., Sanglier-Cianferani, S., Reuter, K., Diederich, F. & Klebe, G. (2013). Launching Spiking Ligands into a Protein Protein Interface : A Promising Strategy To Destabilize and Break Interface Formation in a tRNA Modifying Enzyme. ACS Chem. Biol. 8, 1163-1178. doi :

Laventie, B. J., Potrich, C., Atmanene, C., Saleh, M., Joubert, O., Viero, G., Bachmeyer, C., Antonini, V., Mancini, I., Cianferani-Sanglier, S., Keller, D., Colin, D. A., Bourcier, T., Anderluh, G., Van Dorsselaer, A., Dalla Serra, M. & Prevost, G. (2013). p-Sulfonato-calix n arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions. Biochem. J 450, 559-571. doi :

Mialoundama, A. S., Jadid, N., Brunel, J., Di Pascoli, T., Heintz, D., Erhardt, M., Mutterer, J., Bergdoll, M., Ayoub, D., Van Dorsselaer, A., Rahier, A., Nkeng, P., Geoffroy, P., Miesch, M., Camara, B. & Bouvier, F. (2013). Arabidopsis ERG28 Tethers the Sterol C4-Demethylation Complex to Prevent Accumulation of a Biosynthetic Intermediate That Interferes with Polar Auxin Transport. Plant Cell 25, 4879-4893. doi :

Miguet, L., Lennon, S., Baseggio, L., Traverse-Glehen, A., Berger, F., Perrusson, N., Chenard, M. P., Galoisy, A. C., Eischen, A., Mayeur-Rousse, C., Maar, A., Fornecker, L., Herbrecht, R., Felman, P., Van Dorsselaer, A., Carapito, C., Cianferani, S. & Mauvieux, L. (2013). Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas. Leukemia 27, 1748-1750. doi :

Nchimi-Nono, K., Wegner, K. D., Linden, S., Lecointre, A., Ehret-Sabatier, L., Shakir, S., Hildebrandt, N. & Charbonniere, L. J. (2013). Activated phosphonated trifunctional chelates for highly sensitive lanthanide-based FRET immunoassays applied to total prostate specific antigen detection. Org. Biomol. Chem. 11, 6493-6501. doi :

Pierrat, P., Laverny, G., Creusat, G., Wehrung, P., Strub, J. M., Van Dorsselaer, A., Pons, F., Zuber, G. & Lebeau, L. (2013). Phospholipid-detergent conjugates as novel tools for siRNA delivery. Chem. Eur. J. 19, 2344-2355. doi :

Plumel, M. I., Wasselin, T., Plot, V., Strub, J. M., Van Dorsselaer, A., Carapito, C., Georges, J. Y. & Bertile, F. (2013). Mass Spectrometry-Based Sequencing and SRM-Based Quantitation of Two Novel Vitellogenin Isoforms in the Leatherback Sea Turtle (Dermochelys coriacea). J. Proteom. Res. 12, 4122-4135. doi :

Prakasam, T., Lusi, M., Elhabiri, M., Platas-Iglesias, C., Olsen, J. C., Asfari, Z., Cianferani-Sanglier, S., Debaene, F., Charbonniere, L. J. & Trabolsi, A. (2013). Simultaneous self-assembly of a [2]catenane, a trefoil knot, and a Solomon link from a simple pair of ligands. Angew. Chem. Int. Ed. 52, 9956-9960. doi :

Rejon, J. D., Delalande, F., Schaeffer-Reiss, C., Carapito, C., Zienkiewicz, K., Alche, J. D., Rodriguez-Garcia, M. I., Van Dorsselaer, A. & Castro, A. J. (2013). Proteomics profiling reveals novel proteins and functions of the plant stigma exudate. J. Exp. Bot. 64, 5695-5705. doi :

Triboulet, S., Aude-Garcia, C., Carriere, M., Diemer, H., Proamer, F., Habert, A., Chevallet, M., Collin-Faure, V., Strub, J. M., Hanau, D., Van Dorsselaer, A., Herlin-Boime, N. & Rabilloud, T. (2013). Molecular Responses of Mouse Macrophages to Copper and Copper Oxide Nanoparticles Inferred from Proteomic Analyses. Mol. Cell. Proteomics 12, 3108-3122. doi :

Wagner-Rousset, E., Schaeffer-Reiss, C., Bednarczyk, A., Corvaïa, N., Van Dorsselaer, A. & Beck, A. (2013). NanoLC Chips MS/MS for the Characterization of N-Glycopeptides Generated from Trypsin Digestion of a Monoclonal Antibody Methods Mol. Biol. 988, 81-91. doi :

Walker, R., Gissot, M., Huot, L., Alayi, T. D., Hot, D., Marot, G., Schaeffer-Reiss, C., Van Dorsselaer, A., Kim, K. & Tomavo, S. (2013). Toxoplasma Transcription Factor TgAP2XI-5 Regulates the Expression of Genes Involved in Parasite Virulence and Host Invasion. J. Biol. Chem. 288, 31127-31138. doi :

Yang, Z. B., Eticha, D., Fuhrs, H., Heintz, D., Ayoub, D., Van Dorsselaer, A., Schlingmann, B., Rao, I. M., Braun, H. P. & Horst, W. J. (2013). Proteomic and phosphoproteomic analysis of polyethylene glycol-induced osmotic stress in root tips of common bean (Phaseolus vulgaris L.). J. Exp. Bot. 64, 5569-5586. doi :


Angenieux, C., Waharte, F., Gidon, A., Signorino-Gelo, F., Wurtz, V., Hojeij, R., Proamer, F., Gachet, C., Van Dorsselaer, A., Hanau, D., Salamero, J. & De La Salle, H. (2012). Lysosomal-Associated Transmembrane Protein 5 (LAPTM5) Is a Molecular Partner of CD1e. Plos One 7, e42634. doi :

Atmanene, C., Petiot-Becard, S., Zeyer, D., Van Dorsselaer, A., Hannah, V. V. & Sanglier-Cianferani, S. (2012). Exploring Key Parameters to Detect Subtle Ligand-Induced Protein Conformational Changes Using Traveling Wave Ion Mobility Mass Spectrometry. Anal. Chem. 84, 4703-4710. doi :

Barthelemy, N. R., Bednarczyk, A., Schaeffer-Reiss, C., Jullien, D., Van Dorsselaer, A. & Cavusoglu, N. (2012). Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments. Anal. Biochem. 421, 43-55. doi :

Beck, A., Sanglier-Cianferani, S. & Van Dorsselaer, A. (2012). Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry. Anal. Chem. 84, 4637-4646. doi :

Bui the Thuong, M., Catala, C., Colas, C., Schaeffer, C., Van Dorsselaer, A., Mann, A. & Wagner, A. (2012). Trimethoxyarene as a Highly Ionizable Tag for Reaction Analysis by Atmospheric Pressure Photoionization Mass Spectrometry (APPI/MS) : Exploration of Heterocyclic Synthesis. Eur. J. Org. Chem., 85-92. doi :

Christine, C., Koubemba, M., Shakir, S., Clavier, S., Ehret-Sabatier, L., Saupe, F., Orend, G. & Charbonniere, L. J. (2012). Synthesis of an activated phosphonated bifunctional chelate with potential for PET imaging and radiotherapy. Org. Biomol. Chem. 10, 9183-9190. doi :

Cousido-Siah, A., Ayoub, D., Berberian, G., Bollo, M., Van Dorsselaer, A., Debaene, F., Dipolo, R., Petrova, T., Schulze-Briese, C., Olieric, V., Esteves, A., Mitschler, A., Sanglier-Cianferani, S., Beauge, L. & Podjarny, A. (2012). Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger. Acta Crystallographica Section D Biological Crystallography 68, 1098-1107. doi :

Cousido-Siah, A., Petrova, T., Hazemann, I., Mitschler, A., Ruiz, F. X., Howard, E., Ginell, S., Atmanene, C., Van Dorsselaer, A., Sanglier-Cianferani, S., Joachimiak, A. & Podjarny, A. (2012). Crystal packing modifies ligand binding affinity : The case of aldose reductase. Proteins 80, 2552-2561. doi :

Halter, D., Goulhen-Chollet, F., Gallien, S., Casiot, C., Hamelin, J., Gilard, F., Heintz, D., Schaeffer, C., Carapito, C., Van Dorsselaer, A., Tcherkez, G., Arsene-Ploetze, F. & Bertin, P. N. (2012). In situ proteo-metabolomics reveals metabolite secretion by the acid mine drainage bio-indicator, Euglena mutabilis. Isme Journal 6, 1391-1402. doi :

Heintz, D., Gallien, S., Compagnon, V., Berna, A., Suzuki, M., Yoshida, S., Muranaka, T., Van Dorsselaer, A., Schaeffer, C., Bach, T. J. & Schaller, H. (2012). Phosphoproteome Exploration Reveals a Reformatting of Cellular Processes in Response to Low Sterol Biosynthetic Capacity in Arabidopsis. J. Proteom. Res. 11, 1228-1239. doi :

Laux, A., Delalande, F., Mouheiche, J., Stuber, D., Dorsselaer, A., Bianchi, E., Bezard, E., Poisbeau, P. & Goumon, Y. (2012). Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-1561. doi :

Laux-Biehlmann, A., Grafe, N., Mouheiche, J., Stuber, D., Welters, I. D., Delalande, F., Poisbeau, P., Garnero, P., Metz-Boutigue, M. H., Schneider, F. & Goumon, Y. (2012). Comparison of serum and lithium-heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations. Br. J. Clin. Pharmacol. 74, 381-383. doi :

Lelong, C., Chevallet, M., Diemer, H., Luche, S., Van Dorsselaer, A. & Rabilloud, T. (2012). Improved proteomic analysis of nuclear proteins, as exemplified by the comparison of two myeloid cell lines nuclear proteomes. J. Proteom. 77, 577-602. doi :

Mori, M., Schult-Dietrich, P., Szafarowicz, B., Humbert, N., Debaene, F., Sanglier-Cianferani, S., Dietrich, U., Mely, Y. & Botta, M. (2012). Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein. Virus Res. 169, 377-387. doi :

Patramool, S., Choumet, V., Surasombatpattana, P., Sabatier, L., Thomas, F., Thongrungkiat, S., Rabilloud, T., Boulanger, N., Biron, D. G. & Misse, D. (2012). Update on the proteomics of major arthropod vectors of human and animal pathogens. Proteomics 12, 3510-3523. doi :

Reichardt, F., Chaumande, B., Habold, C., Robin, J. P., Ehret-Sabatier, L., Le Maho, Y., Liewig, N., Angel, F. & Lignot, J. H. (2012). Kaolinite ingestion facilitates restoration of body energy reserves during refeeding after prolonged fasting. Fundam. Clin. Pharmacol. 26, 577-588. doi :

Renouf, B., Soret, C., Saandi, T., Delalande, F., Martin, E., Vanier, M., Duluc, I., Gross, I., Freund, J. N. & Domon-Dell, C. (2012). Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells. Nucleic Acids Res. 40, 3456-3469. doi :

Sloves, P. J., Delhaye, S., Mouveaux, T., Werkmeister, E., Slomianny, C., Hovasse, A., Alayi, T. D., Callebaut, I., Gaji, R. Y., Schaeffer-Reiss, C., Van Dorsselear, A., Carruthers, V. B. & Tomavo, S. (2012). Toxoplasma Sortilin-like Receptor Regulates Protein Transport and Is Essential for Apical Secretory Organelle Biogenesis and Host Infection. Cell Host Microb. 11, 515-527. doi :

Spagnolo, A., Magnin-Robert, M., Alayi, T. D., Cilindre, C., Mercier, L., Schaeffer-Reiss, C., Van Dorsselaer, A., Clement, C. & Fontaine, F. (2012). Physiological Changes in Green Stems of Vitis vinifera L. cv. Chardonnay in Response to Esca Proper and Apoplexy Revealed by Proteomic and Transcriptomic Analyses. J. Proteom. Res. 11, 461-475. doi :

Vercruysse, T., Basta, B., Dehaen, W., Humbert, N., Balzarini, J., Debaene, F., Sanglier-Cianferani, S., Pannecouque, C., Mely, Y. & Daelemans, D. (2012). A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions. Retrovirol. 9, 95. doi :

Voinot, F., Fischer, C., Bœuf, A., Schmidt, C., Delval-Dubois, V., Reichardt, F., Liewig, N., Chaumande, B., Ehret-Sabatier, L., Lignot, J. H. & Angel, F. (2012). Effects of controlled ingestion of kaolinite (5%) on food intake gut morphology and in vitro motility in rats. Fundam. Clin. Pharmacol. 26, 565-576. doi :

Woldt, E., Terrand, J., Mlih, M., Matz, R. L., Bruban, V., Coudane, F., Foppolo, S., El Asmar, Z., Chollet, M. E., Ninio, E., Bednarczyk, A., Thierse, D., Schaeffer, C., Van Dorsselaer, A., Boudier, C., Wahli, W., Chambon, P., Metzger, D., Herz, J. & Boucher, P. (2012). The nuclear hormone receptor PPAR gamma counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells. Nat. Commun. 3, 1077. doi :


Bertile, F. & Raclot, T. (2011). ATGL and HSL are not coordinately regulated in response to fuel partitioning in fasted rats. J. Nutr. Biochem. 22, 372-379. doi :

Bertin, P. N., Heinrich-Salmeron, A., Pelletier, E., Goulhen-Chollet, F., Arsene-Ploetze, F., Gallien, S., Lauga, B., Casiot, C., Calteau, A., Vallenet, D., Bonnefoy, V., Bruneel, O., Chane-Woon-Ming, B., Cleiss-Arnold, J., Duran, R., Elbaz-Poulichet, F., Fonknechten, N., Giloteaux, L., Halter, D., Koechler, S., Marchal, M., Mornico, D., Schaeffer, C., Smith, A. a. T., Van Dorsselaer, A., Weissenbach, J., Medigue, C. & Le Paslier, D. (2011). Metabolic diversity among main microorganisms inside an arsenic-rich ecosystem revealed by meta- and proteo-genomics. Isme Journal 5, 1735-1747. doi :

Bisse, E., Hovasse, A., Preisler-Adams, S., Epting, T., Wagner, O., Kogel, G., Van Dorsselaer, A. & Schaeffer-Reiss, C. (2011). Hb Riesa or beta 93 (F9) Cys -> Ser, a new electrophoretically silent haemoglobin variant interfering with haemoglobin A1c measurement. J. Chromatogr. B 879, 2952-2956. doi :

Boehler, C., Gauthier, L. R., Mortusewicz, O., Biard, D. S., Saliou, J. M., Bresson, A., Sanglier-Cianferani, S., Smith, S., Schreiber, V., Boussin, F. & Dantzer, F. (2011). Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. PNAS 108, 2783-2788. doi :

Borchani, L., Sassi, A., Shahbazzadeh, D., Strub, J. M., Tounsi-Guetteti, H., Boubaker, M. S., Akbari, A., Van Dorsselaer, A. & El Ayeb, M. (2011). Heminecrolysin, the first hemolytic dermonecrotic toxin purified from scorpion venom. Toxicon 58, 130-139. doi :

Bruneel, O., Volant, A., Gallien, S., Chaumande, B., Casiot, C., Carapito, C., Bardil, A., Morin, G., Brown, G. E., Personne, C. J., Le Paslier, D., Schaeffer, C., Van Dorsselaer, A., Bertin, P. N., Elbaz-Poulichet, F. & Arsene-Ploetze, F. (2011). Characterization of the Active Bacterial Community Involved in Natural Attenuation Processes in Arsenic-Rich Creek Sediments. Microb. Ecol. 61, 793-810. doi :

Catusse, J., Meinhard, J., Job, C., Strub, J. M., Fischer, U., Pestsova, E., Westhoff, P., Van Dorsselaer, A. & Job, D. (2011). Proteomics reveals potential biomarkers of seed vigor in sugarbeet. Proteomics 11, 1569-1580. doi :

Charron, G., Doudnikoff, E., Laux, A., Berthet, A., Porras, G., Canron, M. H., Barroso-Chinea, P., Li, Q., Qin, C., Nosten-Bertrand, M., Giros, B., Delalande, F., Van Dorsselaer, A., Vital, A., Goumon, Y. & Bezard, E. (2011). Endogenous morphine-like compound immunoreactivity increases in parkinsonism. Brain 134, 2321-2338. doi :

Chevreux, G., Atmanene, C., Lopez, P., Ouazzani, J., Van Dorsselaer, A., Badet, B., Badet-Denisot, M. A. & Sanglier-Cianferani, S. (2011). Monitoring the Dynamics of Monomer Exchange Using Electrospray Mass Spectrometry : The Case of the Dimeric Glucosamine-6-Phosphate Synthase. J. Am. Soc. Mass. Spectrom. 22, 431-439. doi :

Destouches, D., Page, N., Hamma-Kourbali, Y., Machi, V., Chaloin, O., Frechault, S., Birmpas, C., Katsoris, P., Beyrath, J., Albanese, P., Maurer, M., Carpentier, G., Strub, J. M., Van Dorsselaer, A., Muller, S., Bagnard, D., Briand, J. P. & Courty, J. (2011). A Simple Approach to Cancer Therapy Afforded by Multivalent Pseudopeptides That Target Cell-Surface Nucleoproteins. Cancer Res. 71, 3296-3305. doi :

Eddabra, R., Moussaoui, W., Prevost, G., Delalande, F., Van Dorsselaer, A., Meunier, O., Scheftel, J. M. & Mimouni, R. (2011). Occurrence of Vibrio cholerae non-O1 in three wastewater treatment plants in Agadir (Morocco). World J. Microb. Biot. 27, 1099-1108. doi :

Fauquenoy, S., Hovasse, A., Sloves, P. J., Morelle, W., Ayali, T. D., Slomianny, C., Werkmeister, E., Schaeffer, C., Van Dorsselaer, A. & Tomavo, S. (2011). Unusual N-glycan Structures Required for Trafficking Toxoplasma gondii GAP50 to the Inner Membrane Complex Regulate Host Cell Entry Through Parasite Motility. Mol. Cell. Proteomics 10, M111.008953. doi :

Fournier, I., Gaucher, D., Chich, J. F., Bach, C., Shooshtarizadeh, P., Picaud, S., Bourcier, T., Speeg-Schatz, C., Strub, J. M., Van Dorsselaer, A., Corti, A., Aunis, D. & Metz-Boutigue, M. H. (2011). Processing of chromogranins/secretogranin in patients with diabetic retinopathy. Regul. Peptides 167, 118-124. doi :

Halter, D., Cordi, A., Gribaldo, S., Gallien, S., Goulhen-Chollet, F., Heinrich-Salmeron, A., Carapito, C., Pagnout, C., Montaut, D., Seby, F., Van Dorsselaer, A., Schaeffer, C., Bertin, P. N., Bauda, P. & Arsene-Ploetze, F. (2011). Taxonomic and functional prokaryote diversity in mildly arsenic-contaminated sediments. Res. Microbiol. 162, 877-887. doi :

Herquel, B., Ouararhni, K., Khetchoumian, K., Ignat, M., Teletin, M., Mark, M., Bechade, G., Van Dorsselaer, A., Sanglier-Cianferani, S., Hamiche, A., Cammas, F., Davidson, I. & Losson, R. (2011). Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. PNAS 108, 8212-8217. doi :

Hispard, F., De Vaufleury, A., Schaeffer, C., Scheifler, R., Badot, P. M., Richert, L. & Martin, H. (2011). Differential liver proteome mapping of control and cadmium-fed rats. Ecotoxicol. Environ. Saf. 74, 576-583. doi :

Iehl, J., Holler, M., Nierengarten, J. F., Yoosaf, K., Malicka, J. M., Armaroli, N., Strub, J. M., Van Dorsselaer, A. & Delavaux-Nicot, B. (2011). Photo-induced Energy Transfer in a T-h-Symmetrical Hexakis-adduct of C-60 Substituted with pi-Conjugated Oligomers. Aust. J. Chem. 64, 153-159. doi :

Iehl, J., Vartanian, M., Holler, M., Nierengarten, J. F., Delavaux-Nicot, B., Strub, J. M., Van Dorsselaer, A., Wu, Y. L., Mohanraj, J., Yoosaf, K. & Armaroli, N. (2011). Photoinduced electron transfer in a clicked fullerene-porphyrin conjugate. J. Mater. Chem. 21, 1562-1573. doi :

Jadid, N., Mialoundama, A. S., Heintz, D., Ayoub, D., Erhardt, M., Mutterer, J., Meyer, D., Alioua, A., Van Dorsselaer, A., Rahier, A., Camara, B. & Bouvier, F. (2011). DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 Mediates the Biogenesis of Isoprenyl-Linked Glycans and Influences Development, Stress Response, and Ammonium Hypersensitivity in Arabidopsis. Plant Cell 23, 1985-2005. doi :

Laux, A., Muller, A. H., Miehe, M., Dirrig-Grosch, S., Deloulme, J. C., Delalande, F., Stuber, D., Sage, D., Van Dorsselaer, A., Poisbeau, P., Aunis, D. & Goumon, Y. (2011). Mapping of Endogenous Morphine-Like Compounds in the Adult Mouse Brain : Evidence of Their Localization in Astrocytes and GABAergic Cells. J. Comp. Neurol. 519, 2390-2416. doi :

Losada, S., Sabatier, L., Hammann, P., Guillier, C., Matos, C., Bermudez, H., Lorenzo, M. A. & Noya, O. (2011). A combined proteomic and immunologic approach for the analysis of Schistosoma mansoni cercariae and adult worm protein extracts and the detection of one of the vaccine candidates, Sm28GST, from a Venezuelan parasite isolate. Investigacion Clinica 52, 121-139.

Marchand, V., Santerre, M., Aigueperse, C., Fouillen, L., Saliou, J. M., Van Dorsselaer, A., Sanglier-Cianferani, S., Branlant, C. & Motorin, Y. (2011). Identification of protein partners of the human immunodeficiency virus 1 tat/rev exon 3 leads to the discovery of a new HIV-1 splicing regulator, protein hnRNP K. RNA Biol. 8, 325-342. doi :

Olguin-Lamas, A., Madec, E., Hovasse, A., Werkmeister, E., Callebaut, I., Slomianny, C., Delhaye, S., Mouveaux, T., Schaeffer-Reiss, C., Van Dorsselaer, A. & Tomavo, S. (2011). A Novel Toxoplasma gondii Nuclear Factor TgNF3 Is a Dynamic Chromatin-Associated Component, Modulator of Nucleolar Architecture and Parasite Virulence. Plos Pathogens 7, e1001328. doi :

Rode, C., Gallien, S., Heintz, D., Van Dorsselaer, A., Braun, H. P. & Winkelmann, T. (2011). Enolases : storage compounds in seeds ? Evidence from a proteomic comparison of zygotic and somatic embryos of Cyclamen persicum Mill. Plant Mol. Biol. 75, 305-319. doi :

Van Dorsselaer, A., Carapito, C., Delalande, F., Schaeffer-Reiss, C., Thierse, D., Diemer, H., Mcnair, D. S., Krewski, D. & Cashman, N. R. (2011). Detection of Prion Protein in Urine-Derived Injectable Fertility Products by a Targeted Proteomic Approach. Plos One 6, e17815. doi :


N. Vitale, D. Thierse and M.-F. Bader
Melittin promotes exocytosis in neuroendocrine cells through the activation of phospholipase A(2).
2010,Regulatory Peptides 111-116

A. Charlet, A. H. Muller, A. Laux , V. Kemmel, A. Schweitzer, J. C. Deloulme, D. Stuber, F. Delalande, E. Bianchi, A. Van Dorsselaer, D. Aunis, A. Andrieux, P. Poisbeau and Y. Goumon
Abnormal nociception and opiate sensitivity of STOP null mice exhibiting elevated levels of the endogenous alkaloid morphine.
2010,Mol. Pain,96

A. Gharbi-Ayachi, J.-C. Labbe, A. Burgess, S. Vigneron, J.-M. Strub, E. Brioudes, A. Van-Dorsselaer, A. Castro and T. Lorca
The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

M. Zimmermann, C. Atmanene, Q. Xu, L. Fouillen, A. B. Van Dorsselaer, D., C. Marsol, M. Hibert, S. Sanglier-Cianferani, C. Pigault, L. K. McNamara, D. M. Watterson, J. Haiech and M. C. Kilhoffer
Homodimerization of the death-associated protein kinase catalytic domain : development of a new small molecule fluorescent reporter
2010,PLoS ONE,e14120

G. Budin, M. Moune-Dimala, G. Leriche, J. Saliou, J. Papillon, S. Sanglier-Cianférani, A. Van Dorsselaer, V. Lamour, L. Brino and A. Wagner
Nondenaturing chemical proteomics for protein complex isolation and identification

M. Trabalon, C. Carapito, F. Voinot, J. Martrette, A. Van Dorsselaer, C. Gilbert and F. Bertile
Differences in Brachypelma albopilosa (theraphosidae) hemolymph proteome between subadult and adult females.
2010,J. Exp. Zool. A Ecol. Genet. Physiol.,651-659

D. Chaix, M. Ferguson, C. Atmanene, A. Van Dorsselaer, S. Sanglier-Cianferani, C. Royer and N. Declerck
Physical basis of the inducer-dependent cooperativity of the CggR repressor/DNA complex
2010,Nucleic Acids Res.,5944-5957

K. Eckert, J. Saliou, L. Monlezun, A. Vigouroux, N. Atmane, C. Caillat, S. Quevillon-Chéruel, K. Madiona, M. Niçaise, S. Lazereg, A. Van Dorsselaer, S. Sanglier-Cianférani, P. Meyer and S. Moréra
The Pih1-Tah1 cochaperone complex inhibits Hsp90 molecular chaperone ATPase activity.
2010,J. Biol. Chem.,31304-31312

R. Mastrangeli, C. Carapito, C. Schaeffer-Reiss, D. Thierse, H. Diemer, R. Sanvito and A. Van Dorsselaer
Prion protein identified in urinary gonadotrophin preparation
2010,Reproductive Medecine and Endocrinology 277

L. Fouillen, W. Abdulrahman, D. Moras, A. Van Dorsselaer, A. Poterszman and S. Sanglier-Cianférani
Analysis of recombinant phosphoprotein complexes with complementary mass spectrometry approaches
2010,Anal. Biochem.,34-43

H. Fuhrs, C. Behrens, S. Gallien, D. Heintz, A. Van Dorsselaer, H.-P. Braun and W. J. Horst
Physiological and proteomic characterization of manganese sensitivity and
tolerance in rice (Oryza sativa) in comparison with barley (Hordeum vulgare)

2010,Ann. Bot.,1129-40

B. Ossareh-Nazari, M. Bonizec, M. Cohen, S. Dokudovskaya, F. Delalande, C. Schaeffer, A. Van Dorsselaer and C. Dargemont
Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy
2010,EMBO Rep.,548-54

S. Revollon, J. Strub, A. Fitchette, L. Wiss, V. Gomord, A. Van Dorsselaer and V. Brault
A reinvestigation provides no evidence for sugar residues on structural proteins of poleroviruses and argues against a role for glycosylation of virus structural proteins in aphid transmission

C. Atmanene, D. Chaix, Y. Bessin, N. Declerck, A. Van Dorsselaer and S. Sanglier-Cianferani
Combination of Noncovalent Mass Spectrometry and Traveling Wave Ion Mobility Spectrometry Reveals Sugar-Induced Conformational Changes of CggR / DNA Complex
2010,Anal. Chem.,3597-605

H. Samaha, V. Delorme, F. Pontvianne, R. Cooke, F. Delalande, A. Van Dorsselaer, M. Echeverria and J. Saez Vasquez
Identification of protein factors and U3 snoRNAs from a B. oleracea RNP complex involved in processing of pre-rRNA
2010,Plant Journal,383-98

L. Babujee, V. Wurtz, C. Ma, F. Lueder, P. Soni, A. Van Dorsselaer and S. Reumann
The proteome map of spinach leaf peroxisomes indicates partial compartmentalization of phylloquinone (vitamin K1) biosynthesis in plant peroxisomes.
2010,J. Exp. Bot. ,1441-53

A. Castro, A. Bednarczyk, C. Schaeffer-Reiss, M. Rodríguez-García, A. van Dorsselaer and J. de Dios Alché
Screening of Ole e 1 polymorphism among olive cultivars by peptide mapping and N-glycopeptide analysis.

A. Akaddar, C. Doderer-Lang, M. R. Marzahn, F. Delalande, M. Mousli, K. Helle, A. Van Dorsselaer, D. Aunis, B. M. Dunn, M.-H. Metz-Boutigue and E. Candolfi
Catestatin, an endogenous Chromogranin A–derived peptide, inhibits in vitro growth of Plasmodium falciparum
2010,Cell. Mol. Life Sci.,1005-15

E. Glattard, I. D. Welters, T. Lavaux, A. H. Muller, A. Laux, D. Zhang, A. R. Schmidt, F. Delalande, B. J. Laventie, S. Dirrig-Grosch, D. A. Colin, A. Van Dorsselaer, D. Aunis, M. H. Metz-Boutigue, F. Schneider and Y. Goumon
Endogenous morphine levels are increased in sepsis : a partial implication of neutrophils.
2010,PLoS ONE,e8791.

Y. Kuhn, C. Sanchez, D. Ayoub, T. Saridaki, A. van Dorsselaer and M. Lanzer
Trafficking of the Phosphoprotein PfCRT to the Digestive Vacuolar Membrane in Plasmodium falciparum.

S. Maenner, M. Blaud, L. Fouillen, A. Savoye, V. Marchand, A. Dubois, S. Sanglier-Cianférani, A. Van Dorsselaer, P. Clerc, P. Avner, A. Visvikis and C. Branlant
2D structure of the A region of Xist RNA and its implication for PRC2 association
2010,PLoS Biol. ,e1000276

V. Vivat Hannah, C. Atmanene, D. Zeyer, A. Van Dorsselaer and S. Sanglier-Cianférani
Native MS : an ‘ESI’ way to support structure- and fragment-based drug discovery
2010,Future Med. Chem.,35-50