DRHIM | Imagerie Moléculaire » Equipe » Ali OUADI

Ali OUADI

Dernière mise à jour : mardi 4 août 2020, par Catherine Berger

Academic organism : CNRS

Phone : +33 (0)3 88 10 66 75

Fax : +33 (0)3 88 10 64 31

E-mail :

Express biography

  • Since 2003 : Research engineer, Institut Pluridisciplinaire Hubert Curien (UMR 7178), Imagerie Moléculaire (Strasbourg, France).
  • 2000-2003 : Scientific officer at Transuranium Institute (ITU) European Commission, Joint research Center (Karlsruhe , Germany)
    Research area : Radium-223 for alpha-immunotherapy
  • 1996-2000 : PhD thesis in Chemistry and radiochemistry (Nantes University / Subatech , France)
    Research area : Actinium-225 for alpha-immunotherapy
  • 1995 : Master in Radiochemistry and radiopharmaceuticals (Grenoble University, France)

Research interests

  • Radioelements production and purification
  • Design and synthesis of novel ligands for SPECT and PET imaging
  • Radiolabeling
  • Antibodies, peptides
  • Tc-99m, I-123, F-18, Zr-89, Cu-64, Ga-68, Ra-223, Ac-225
  • Radiochemistry
  • Task specific ionic liquids synthesis

Keywords : PET and SPECT radiopharmaceuticals, radiolabeling, ionic liquids

Bibliography

47. scientific papers in ISI-refereed International Journals with a total number of citations > 1400 and an h-factor of 19 (data from Google Scholar).

Selected publications :

1. Ouadi, A ; Bekaert, Virgile et al.(2018).” Imaging thrombosis with Tc-99m-labeled RAM.1-antibody in vivo” Nuclear Medicine and Biology 61 : 21-27.

2. Maisonial-Besset, A ; Serre, A ; Ouadi, A ; et al. (2018) Base/Cryptand/Metal-Free
Automated Nucleophilic Radiofluorination of [F-18]FDOPA from Iodonium Salts :
Importance of Hydrogen Carbonate Counterion Eur. J. Org. Chem 48, 7058-7065

3. P. Marchand., A. Ouadi, et al. (2016). "Automated and efficient radiosynthesis of F-18 FLT using a low amount of precursor." Nuclear Medicine and Biology 43(8) : 520-527.

4. S. Abada, A.Ouadi et al. (2014). "Phosphonated chelates for nuclear imaging." Organic &
Biomolecular Chemistry 12(47) : 9601-9620.

5. P. Marchand, A. Ouadi et al. (2013). "Forty Years of F-18-Labeled Compound
Development in an Open Access Database." Journal of Nuclear Medicine 54(1) : 15N-+.

6. A. Ouadi, C. Habold, et al. (2013). "Synthesis of new I-123-labeled free fatty acids analogues
and first evaluation as potential tracers for SPECT imaging to elucidate fatty acid flux in
mouse." Rsc Advances 3(41) : 19040-19050.

7. T. Devarasu, A. Ouadi et al. (2013). "Potent calcium phosphate nanoparticle surface coating for in vitro and in vivo siRNA delivery : a step toward multifunctional nanovectors." Journal of Materials Chemistry B 1(36) : 4692-4700.